Selective recognition of unnatural imidazopyridopyrimidine:naphthyridine base pairs consisting of four hydrogen bonds by the Klenow fragment

Journal of the American Chemical Society
Noriaki MinakawaAkira Matsuda

Abstract

In this work, we investigated how thermally stable ImO(N):NaN(O) and ImN(O):NaO(N) pairs are recognized by the Klenow fragment (KF). As a result, these complementary base pairs, especially the ImN(O):NaO(N) pair, were recognized selectively due to the four hydrogen bonds between the nucleobases and the shape complementarity of the Im:Na pair similar to the purine:pyrimidine base pair.

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Citations

Oct 16, 2015·Chemical Communications : Chem Comm·Yoshiyuki TanakaAkira Ono
Apr 6, 2011·Expert Review of Molecular Diagnostics·Michiko KimotoIchiro Hirao
Sep 26, 2009·Chembiochem : a European Journal of Chemical Biology·Haige LuEric T Kool
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Nov 20, 2013·Angewandte Chemie·Malte Winnacker, Eric T Kool
Jul 16, 2015·Chemistry : a European Journal·Noriko TarashimaNoriaki Minakawa
Feb 2, 2018·Chemical & Pharmaceutical Bulletin·Noriko Saito-Tarashima, Noriaki Minakawa
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Sep 24, 2019·Chemistry : a European Journal·Andreas Marx, Karin Betz
Jan 30, 2020·Nucleosides, Nucleotides & Nucleic Acids·Koki MatsumotoNoriaki Minakawa
Jun 18, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Xin GanWen-Fu Fu
May 31, 2012·Angewandte Chemie·Tatsuya FunaiHidehito Urata
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Nov 29, 2013·Journal of the American Chemical Society·Karin BetzAndreas Marx
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