Selective removal of anti-double-stranded DNA antibodies by immunoadsorption with dextran sulphate in a patient with systemic lupus erythematosus.

Annals of the Rheumatic Diseases
M KinoshitaR Yokohari

Abstract

A dextran sulphate gel column removed anti-double-stranded DNA antibodies (anti-dsDNA) selectively, efficiently, and safely from the circulation of a patient with systemic lupus erythematosus (SLE). The mechanism of the removal is thought to be due to cross reactivity of anti-dsDNA with dextran sulphate, which has negatively charged units. Selective removal of anti-dsDNA is expected to contribute not only to the treatment but also to elucidation of the pathogenesis of SLE.

References

Jan 1, 1979·Journal of Immunological Methods·S AotsukaR Yokohari
Nov 1, 1985·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·S YokoyamaA Yamamoto
Sep 16, 1981·Biochemical and Biophysical Research Communications·P J White, S O Hoch
Jan 1, 1984·Clinical Immunology and Immunopathology·S UwatokoK Suzuki

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Citations

Jun 1, 1993·Lupus·D J Wallace
Mar 20, 2002·Acta medica Austriaca·Monika GraningerW B Graninger
Sep 15, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Feng LiuLeaf Huang
Jan 22, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Hans-Joachim AndersDetlef Schlöndorff
May 1, 1997·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·M SchneiderA Perniok
May 5, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·H HashimotoT Nagasawa
Feb 1, 1990·Clinical and Experimental Immunology·S AotsukaR Yokohari
Mar 18, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·T HidakaH Kutsuki
Aug 16, 2003·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Markus Gaubitz, K Matthias Schneider
Mar 1, 1992·Annals of the Rheumatic Diseases·S KobayashiS Hirose
Jul 26, 2000·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·K Suzuki
May 5, 1999·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·H KutsukiN Tani
Dec 4, 2002·Therapeutic Apheresis : Official Journal of the International Society for Apheresis and the Japanese Society for Apheresis·Norbert BraunTeut Risler

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