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Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models

Translational Vision Science & Technology

Nov 1, 2019

Jan TodeJohann B Roider

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Abstract

To investigate the effect of selective retina therapy (SRT) on age-related macular degeneration (AMD)-like alterations of retinal pigment epithelium (RPE) and Bruch's membrane (BrM) in AMD mouse models as therapeutic approach for the treatment of dry AMD. In B6.129P2-Apoetm1Unc /J (ApoE...read more

Mentioned in this Paper

Apolipoprotein E
Enucleation Procedure
Eye
Glycogen Storage Disease Type II
Laboratory mice
Microvilli
Pigment
Randomization
Structure of Retinal Pigment Epithelium
Vacuole
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Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models

Translational Vision Science & Technology

Nov 1, 2019

Jan TodeJohann B Roider

PMID: 31737435

DOI: 10.1167/tvst.8.6.11

Abstract

To investigate the effect of selective retina therapy (SRT) on age-related macular degeneration (AMD)-like alterations of retinal pigment epithelium (RPE) and Bruch's membrane (BrM) in AMD mouse models as therapeutic approach for the treatment of dry AMD. In B6.129P2-Apoetm1Unc /J (ApoE...read more

Mentioned in this Paper

Apolipoprotein E
Enucleation Procedure
Eye
Glycogen Storage Disease Type II
Laboratory mice

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