Selective role for striatal and prefrontal regions in processing first trial feedback during single-trial associative learning.

Brain Research
James C EliassenStephen M Strakowski

Abstract

Discrete jumps in knowledge, as exemplified by single-trial learning, are critical to survival. Despite its importance, however, one-trial learning remains understudied. We sought to better understand the brain activity adaptations that track punctuated changes in associative knowledge by studying visual-motor associative learning with functional magnetic resonance imaging. Human and primate neurophysiological studies of feedback-based learning indicate that performance feedback elicits high activity at first that diminishes rapidly with repeated success. Based on these findings we hypothesized a network of brain regions would track the importance of feedback, which is large early in learning and diminishes thereafter. Specifically, based on neurophysiological findings, we predicted that frontal and striatal regions would show a large activation to first trial feedback and a subsequent reduction selective to performance feedback but not stimulus cue presentation. We observed that the striatum and frontal cortex as well as several other cortical and subcortical sites exhibited this pattern. These findings match our prediction for activity in frontal and striatal regions. Furthermore, these observations support the more general h...Continue Reading

References

Jun 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·K K KwongR Turner
Jul 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·S OgawaK Ugurbil
Sep 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J H LeeK Uğurbil
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S D FormanD C Noll
Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
Mar 14, 1997·Science·W SchultzP R Montague
Jun 1, 1997·NMR in Biomedicine·R W Cox, J S Hyde
Nov 26, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R W Cox, A Jesmanowicz
Jul 27, 2000·Human Brain Mapping·J L LancasterP T Fox
Jul 5, 2001·IEEE Transactions on Medical Imaging·V J SchmithorstS K Holland
Nov 21, 2001·Experimental Brain Research·J C EliassenJ N Sanes
Dec 6, 2001·Nature·R A PoldrackM A Gluck
May 29, 2002·Proceedings of the National Academy of Sciences of the United States of America·Seiki KonishiYasushi Miyashita
Oct 24, 2002·Neuroreport·Francisco BarcelóRobert T Knight
Mar 11, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Charlotte A Boettiger, Mark D'Esposito
Apr 27, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xun LiuJane E Joseph
Sep 19, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Anna C K van DuijvenvoordeEveline A Crone
Oct 7, 2008·NeuroImage·Amanda Bischoff-GretheScott T Grafton
Apr 4, 2009·NeuroImage·Patrick Bédard, Jerome N Sanes
Jun 15, 2011·NeuroImage·Andrea BrovelliDriss Boussaoud
Jan 1, 1994·Human Brain Mapping·K J FristonA C Evans

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Citations

Feb 26, 2014·Journal of Cognitive Neuroscience·Sabine PetersEveline A Crone
Jul 31, 2013·Neuroscience·M VinkT E Gladwin
Jul 23, 2014·Neuropsychologia·Sabine PetersMaartje E J Raijmakers

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