Selective site pacing: rationale and practical application.

Current Cardiology Reports
Sameer Parekh, Kenneth M Stein

Abstract

Although it has become traditional to place permanent pacemaker leads at the right ventricular apex and right atrial appendage, pacing from these locations poorly mimics normal physiology. A growing evidence base shows that right ventricular apical pacing results in ventricular dyssynchrony and various adverse effects. Provocative data from early trials suggest that pacing from alternate sites in the right ventricle--His bundle pacing, para-Hisian pacing, septal right ventricular outflow tract pacing, and right ventricular midseptal pacing--may lead to improved results. Similarly, early data suggest that right atrial pacing near Bachmann's bundle may lead to superior outcomes when compared with pacing from the right atrial appendage. Several large-scale, randomized clinical trials are now under way to establish the future role of selective site pacing.

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Citations

Dec 25, 2008·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Rong BaiWee Siong Teo
Jul 11, 2009·Expert Review of Cardiovascular Therapy·José Carlos Pachón MateosJuán Carlos Pachón Mateos

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