Selective transport of an oligomeric IgA into canine saliva

Immunological Communications
P C MontgomeryG Virella

Abstract

Evidence is presented which shows that an oligomeric IgA myeloma protein possessing J-chain but lacking secretory component, is selectively transferred from serum into canine saliva. The data also demonstrate that 125I-label remains with the IgA during the transfer process. These data interpreted in the light of findings in humans support the concept that the oligomeric form of IgA, devoid of secretory component, is required to achieve selective transport.

References

Jan 1, 1976·Advances in Immunology·M E Lamm
Jan 1, 1977·International Archives of Allergy and Applied Immunology·G VirellaJ Goudswaard
Sep 1, 1976·Proceedings of the Society for Experimental Biology and Medicine·J A KazmierowskiH Y Reynolds
Aug 1, 1975·British Journal of Haematology·G VirellaF Graça
Dec 1, 1967·The Journal of Clinical Investigation·W T ButlerT A Waldmann
Nov 1, 1969·Immunochemistry·J P Vaerman, J F Heremans
Aug 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·D F SummersJ E Darnell
Sep 1, 1974·Journal of Speech and Hearing Research·S I Ritterman, N C Freeman
Mar 1, 1972·Nature: New Biology·R M Parkhouse
Apr 15, 1973·Experientia·G Virella
Jan 1, 1965·The Journal of Experimental Medicine·T B TOMASIR A PRENDERGAST

Citations

Dec 1, 1981·Journal of Steroid Biochemistry·D A Sullivan, C R Wira
Jan 1, 1979·Comparative Immunology, Microbiology and Infectious Diseases·J GoudswaardJ A van der Donk
Jan 1, 2004·Veterinary Immunology and Immunopathology·Harm HogenEschMichael Hayek
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M M FisherB J Underdown
May 1, 1984·The Journal of Experimental Medicine·R A Allardyce
Aug 1, 1982·Australian and New Zealand Journal of Medicine·M GleesonS R Leeder
Jul 1, 1981·Scandinavian Journal of Immunology·U DahlgrenL A Hanson
Jan 1, 1985·Acta Pathologica Japonica·H SaitoH Nagura
May 1, 1982·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J S DooleyS Sherlock
Jan 1, 1982·Immunological Communications·I Lemaître-CoelhoJ P Vaerman

Related Concepts

Cryoproteins
Canis familiaris
SDS-PAGE
IgA2
Total Body Clearance Rate
Saliva
Plasma Albumin

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