Selective venous sampling for androgen-producing ovarian pathology.

Clinical Endocrinology
Eric D LevensLynnette K Nieman

Abstract

Multiple diagnostic modalities may be needed to establish the source of excessive androgen production in women. The role of selective venous catheterization in this process has not been established fully. A study of hyperandrogenaemic subjects and literature review. Four hyperandrogenaemic women and an additional 132 previously reported cases with available testing data and a pathological diagnosis were evaluated. Serum androgens, diagnostic imaging and ovarian venous effluent sampling. Criteria to distinguish ovarian tumours from other ovarian conditions and to localize the lesion(s) were evaluated. Basal peripheral testosterone levels >or= 4.51 nmol/l (>or= 130 ng/dl) discriminated ovarian tumours from benign causes of hyperandrogenism (sensitivity: 93.8%, 95% CI 85.0-98.2; specificity: 77.8%, 95% CI 66.4-86.7). Single lesions produced higher ipsilateral testosterone concentrations (612.6 +/- 162.0 nmol/l; 17 653 +/- 4670 ng/dl) compared to contralateral values (26.4 +/- 5.2 nmol/l; 761 +/- 150 ng/dl). In women with peripheral testosterone >or= 4.51 nmol/l, a right-to-left (R:L) ovarian testosterone ratio >or= 1.44 correctly identified all 18 women with right-sided tumours and misclassified two with bilateral lesions; 12 out ...Continue Reading

References

Jul 1, 1978·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·V A TzingounisR B Greenblatt
Sep 1, 1979·The Journal of Clinical Endocrinology and Metabolism·N G BaranetskyF Z Stanczyk
Sep 1, 1977·American Journal of Obstetrics and Gynecology·S CasthelyR Pierre-Louis
Aug 1, 1976·American Journal of Obstetrics and Gynecology·A C WentzG S Jones
Apr 1, 1992·Acta Obstetricia Et Gynecologica Scandinavica·I CohenY Beyth
Dec 1, 1991·Journal of Endocrinological Investigation·C BricaireP Mauvais-Jarvis
Jul 1, 1990·The Journal of Clinical Endocrinology and Metabolism·D A Ehrmann, R L Rosenfield
Jan 1, 1986·Cardiovascular and Interventional Radiology·R SörensenU Schwartz
Dec 1, 1988·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·C van HeyningenD Tuffnell
Aug 1, 1971·The Journal of Clinical Endocrinology and Metabolism·M A Kirschner, J B Jacobs
Dec 1, 1981·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H M HenriksenE Guttorm
Nov 30, 1999·The Journal of Obstetrics and Gynaecology Research·Y InoueH Nakano
Jun 4, 2002·Human Reproduction·J W StephensP-M G Bouloux
Aug 24, 2002·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·E CserepesK Rácz
Feb 13, 2003·The Australasian Journal of Dermatology·Youngjin KimDedee Murrell
Oct 8, 2003·Gynecologic Oncology·L C WhiteR Boothby
Feb 7, 2004·The Journal of Clinical Endocrinology and Metabolism·R AzzizL R Boots
Oct 27, 2004·AJR. American Journal of Roentgenology·Tadao HiromuraKazuo Tomita
Jul 13, 2005·Fertility and Sterility·Ryan D DickersonAnil B Pinto
Dec 1, 2005·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·L G NardoM W Seif
Dec 13, 2005·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Michael K BohlmannMichael Von Wolff
Dec 5, 2006·Current Opinion in Urology·Gertraud Heinz-PeerBruno Niederle
Mar 9, 2007·Medizinische Klinik·Anna MatuszczykKlaus Mann
May 24, 2007·The Journal of Clinical Endocrinology and Metabolism·Robin H FogleRichard J Paulson

❮ Previous
Next ❯

Citations

Oct 5, 2013·Endocrine·Rosa Maria ParagliolaSalvatore M Corsello
Jul 22, 2014·Case Reports in Endocrinology·Jaya M MehtaSerge A Jabbour
Jul 31, 2013·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·María Rosario Vallejo MoraStella González Romero
Oct 23, 2012·Journal of Minimally Invasive Gynecology·Caitlin Dunne, Jon C Havelock
Feb 18, 2012·Gynécologie, obstétrique & fertilité·A-L CastellP Fénichel
Feb 26, 2015·Revista clínica española·S Herranz-AntolínJ V Del Cerro-González
Mar 31, 2015·Annales de dermatologie et de vénéréologie·E BahloulH Turki
Jan 13, 2015·Case Reports in Endocrinology·Murat AtmacaYasin Sezgin
Jun 30, 2016·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Dimitra BogdanouJoerg Bojunga
Jul 19, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·B P JonesJ Yazbek
Jul 12, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Eric J MonroeKarim Valji
Feb 16, 2011·Nature Reviews. Endocrinology·André M FariaMaria A A Pereira
Aug 17, 2011·Current Opinion in Endocrinology, Diabetes, and Obesity·Chirag Patel, Matthew Matson
Sep 30, 2020·Journal of Women's Health·Alexis LeVeeChrisandra Shufelt
May 30, 2019·Obstetrics & Gynecology Science·Jinkyoung KongJoo Hyun Park
May 15, 2018·Journal of Clinical Medicine·Ryan W EnglandAmy R Deipolyi
Dec 16, 2020·BMJ Case Reports·Chin Voon Tong, Yong Ting Tai
Dec 17, 2020·Journal of the Endocrine Society·Eng-Loon Tng, Jeanne May May Tan
Jun 18, 2021·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·S Ahmed HussainMichael Johnston
Jul 27, 2021·AACE Clinical Case Reports·Jane E DrianoAida N Lteif
Aug 4, 2021·Pediatrics in Review·Brittany S Bruggeman, Angelina Bernier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
E K OutwaterB J Wagner
Journal of Computer Assisted Tomography
Andrew B RosenkrantzElizabeth M Hecht
Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Vasileios PrassopoulosJohn Andreou
© 2022 Meta ULC. All rights reserved