Selective versus comprehensive neck dissection after chemoradiation for advanced oropharyngeal squamous cell carcinoma.

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Alexander T HillelPatrick K Ha

Abstract

To determine whether a comprehensive neck dissection (CND) or a selective neck dissection (SND) is indicated as planned post-primary chemoradiation treatment (CRT) for patients with advanced oropharyngeal squamous cell carcinoma (OPSCC). Case series with chart review. A community teaching hospital. Patients with advanced OPSCC who received a uniform CRT protocol at Greater Baltimore Medical Center (GBMC). Medical records of patients treated with primary CRT for locoregionally advanced OPSCC at GBMC between 2001 and 2007 were reviewed. All patients received 7000 to 7500, 6000, and 5000 cGy to primary disease sites, involved cervical lymphatics, and uninvolved cervical and supraclavicular lymphatics, respectively, with concomitant cisplatin (12 mg/m(2)/1 h) and 5-fluorouracil (600 mg/m(2)/20 h) given on days one through five and 29 through 33. Seventy-six patients received CRT, and 41 met the criteria for neck dissection. Forty-eight neck dissections were performed (34 unilateral and 7 bilateral), of which 23 (48%) were CNDs and 25 (52%) were SNDs. Residual carcinoma was found in six (26%) of the CND and five (20%) of the SND heminecks. The CND group had six (26%) complications, whereas the SND group had two (8%). The high rate o...Continue Reading

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Citations

Aug 21, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Laura A GoguenDonald J Annino
Sep 20, 2012·The Journal of Laryngology and Otology·J G SandersJ White
Mar 10, 2012·Annals of Surgical Oncology·Juliette ThariatXavier Dufour
Aug 26, 2014·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Raul PelliniGiuseppe Spriano
Sep 18, 2014·Current Treatment Options in Oncology·Marc HamoirVincent Gregoire
Aug 21, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·K Thomas RobbinsJesus E Medina
Oct 4, 2015·The British Journal of Oral & Maxillofacial Surgery·Ben GreenPeter A Brennan
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Jan 11, 2016·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A ModestoM Rives
Feb 12, 2011·International Journal of Radiation Oncology, Biology, Physics·Sébastien ClavelPhuc Felix Nguyen-Tan
Jun 28, 2014·International Journal of Oncology·Masahiro HasegawaMikio Suzuki
Dec 4, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Roel HennemanAlfons Jm Balm

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Methods Mentioned

BETA
dissection
biopsy
dissections

Software Mentioned

MedCalc

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