Selective versus nonselective thoracic fusion in Lenke 1C curves: a meta-analysis of baseline characteristics and postoperative outcomes

Journal of Neurosurgery. Spine
Anthony J BonielloPeter G Passias

Abstract

Lenke 1C curves are challenging to manage surgically due to the structural thoracic deformity and nonstructural lumbar curve. Selective thoracic fusion (STF) is considered the standard of care because it preserves motion of the lumbar segment, yet nonselective STF (NSTF) remains prevalent. This study aims to identify baseline patient characteristics that drive treatment and to compare postoperative outcomes for both procedures. Studies that compared baseline and postoperative demographic data, health-related quality of life (HRQL) questionnaires, and radiographic parameters of patients with Lenke 1C curves undergoing STF or NSTF were identified for meta-analysis. The effect measure is expressed as a mean difference (MD) with 95% CI. A positive MD signifies a greater STF value, or a mean increase within the group. One prospective and 6 retrospective case-control studies with sample size of 488 patients (344 STF and 144 NSTF) were identified. Baseline age, sex, and HRQLs were equivalent, except for better scores in the STF group for the Scoliosis Appearance Questionnaire (SAQ): Unrelated to Deformity item (3.47 vs 3.88, p = 0.01) and the Spine Research Society questionnaire, Item 22: Pain (4.13 vs 3.92, p = 0.04). Radiographic fi...Continue Reading

References

Jul 1, 1992·Journal of Pediatric Orthopedics·R E McCall, W Bronson
Aug 1, 1995·The Journal of Bone and Joint Surgery. American Volume·P J ConnollyJ P Kostuik
Jan 1, 1996·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·I T BenliR Tandoğan
Jan 1, 1996·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·A J HosmanW J Beijneveld
May 24, 2000·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·V ArletM Aebi
Feb 13, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Rob C JansenAndré van Ooij
Oct 20, 2007·The Orthopedic Clinics of North America·B Stephens Richards
Jan 5, 2011·Journal of Pediatric Orthopedics·Meghan ImriePeter O Newton
May 3, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Per D TrobischPatrick J Cahill
Dec 6, 2011·The Spine Journal : Official Journal of the North American Spine Society·Yu WangEbbe S Hansen
Apr 26, 2012·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ulf LiljenqvistViola Bullmann
Feb 23, 2013·Spine·Satoru DemuraUNKNOWN Harms Study Group
May 2, 2013·Spine·Charles H CrawfordJames O Sanders

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Citations

Sep 21, 2016·Scoliosis and Spinal Disorders·Federico Balagué, Ferran Pellisé
May 27, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Laura ScaramuzzoAntonino Zagra
Jun 12, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·T Barrett SullivanBurt Yaszay
Jun 27, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·H KollerP O Newton
Apr 12, 2019·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·S TournemineB Ilharreborde
Jun 19, 2021·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Federico SollaCarlo M Bertoncelli

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