Selectivity and persistent firing responses to social vocalizations in the basolateral amygdala.

Neuroscience
D C Peterson, Jeffrey J Wenstrup

Abstract

This study examined responsiveness to acoustic stimuli among neurons of the basolateral amygdala. While recording from single neurons in awake mustached bats (Pteronotus parnellii), we presented a wide range of acoustic stimuli including tonal, noise, and vocal signals. While many neurons displayed phasic or sustained responses locked to effective auditory stimuli, the majority of neurons (n=58) displayed a persistent excitatory discharge that lasted well beyond stimulus duration and filled the interval between successive stimuli. Persistent firing usually began seconds (median value, 5.4 s) after the initiation of a train of repeated stimuli and lasted, in the majority of neurons, for at least 2 min after the end of the stimulus train. Auditory-responsive amygdalar neurons were generally excited by one stimulus or very few stimuli. Most neurons did not respond well to synthetic stimuli including tones, noise bursts or frequency-modulated sweeps, but instead responded only to vocal stimuli (82 of 87 neurons). Furthermore, most neurons were highly selective among vocal stimuli. On average, neurons responded to 1.7 of 15 different syllables or syllable sequences. The largest percentage of neurons responded to a hiss-like rectangu...Continue Reading

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Citations

Dec 20, 2012·PloS One·Jasmine M S GrimsleyMark N Wallace
Sep 6, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ian C HallDarcy B Kelley
Jul 15, 2015·Hearing Research·Alessia PanneseSascha Frühholz
Feb 21, 2019·Journal of Neurophysiology·Stephen Gareth Hörpel, Uwe Firzlaff
Nov 6, 2015·Journal of Neurophysiology·Marie A GadziolaJeffrey James Wenstrup
Feb 8, 2021·Current Opinion in Neurobiology·Ofer Yizhar, Dana R Levy
Aug 25, 2021·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Koilmani Emmanuvel Rajan

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