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Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors

British Journal of Pharmacology

May 1, 1977

J C DoxeyJ Michael Walker

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Abstract

1. Low frequency (0.1 Hz) electrical stimulation of the rat isolated vas deferens produced regular contractions that were inhibited by low concentrations of clonidine. 2. The inhibition of the vas deferens produced by clonidine was presynaptic in origin and involved alpha-adrenoceptors....read more

Mentioned in this Paper

Vas Deferens Structure
Synapses
Smooth Muscle
Z-Max
Isoglaucon
Norepinephrine
Norepinephrine, (+, -)-Isomer
Structure of Anococcygeal Nerve
Metazoa
Metabolic Inhibition
Paper Details
References
    • References8
    • Citations205
    • References8
    • Citations205
  • Selectivity of blocking agents for pre-and postsynaptic alpha-adrenoceptors

    British Journal of Pharmacology

    May 1, 1977

    J C DoxeyJ Michael Walker

    PMID: 18248

    DOI: 10.1111/j.1476-5381.1977.tb16752.x

    Abstract

    1. Low frequency (0.1 Hz) electrical stimulation of the rat isolated vas deferens produced regular contractions that were inhibited by low concentrations of clonidine. 2. The inhibition of the vas deferens produced by clonidine was presynaptic in origin and involved alpha-adrenoceptors....read more

    Mentioned in this Paper

    Vas Deferens Structure
    Synapses
    Smooth Muscle
    Z-Max
    Isoglaucon

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    Paper Details
    References
    • References8
    • Citations205
    • References8
    • Citations205
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