Selenium and vitamins status in Saudi children

Clinica Chimica Acta; International Journal of Clinical Chemistry
Iman Al-SalehGamal Yosef

Abstract

Selenium is an essential element, and a cofactor required to maintain glutathione peroxidase activity. Its deficiency may induce modification in the cellular antioxidative status and the appearance of different diseases. Previous studies in Al-Kharj reported low selenium levels in the soil and the milk of lactating mothers living in that area. A cross-sectional study was carried out to determine the status of selenium, dl-alpha-tocopherol, and all-trans-retinol in 513 Saudi children living in Al-Kharj district using serum and toenail samples. The prevalence of children with serum selenium below the threshold limit of clinical importance in coronary and cardiovascular diseases (45 microg/l) was only 1.4%, while 53.4% of the tested children had toenail selenium >0.56 microg/g, which is considered a low level as indicated in a previous study. DL-alpha-tocopherol deficiency (<0.5 mg/dl) was found only in 3.1%. However, none of the children in this study had a severe all-trans-retinol deficiency (<10 microg/dl) and the percentage of children with marginal deficiency <20 microg/dl was 5.5%. It seems that the geographical location of primary health care units (PHCUs) is the most important factor in influencing the selenium status of t...Continue Reading

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Citations

Mar 28, 2013·BMC Pediatrics·Abdulrahman Al-MataryJaffar Ali
Dec 5, 2009·Critical Reviews in Clinical Laboratory Sciences·Daniela GiustariniRanieri Rossi
May 18, 2013·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·B NaviaE Rodríguez-Rodríguez
Jun 30, 2019·Nutrients·Sohayla A Z IbrahimAbdelali Agouni
May 28, 2019·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Anku MalikGeeta Trilok-Kumar

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