PMID: 2484513Jan 1, 1988Paper

Selenium in total parenteral nutrition

Biological Trace Element Research
H B von Stockhausen

Abstract

In clinical practice, selenium deficiency may arise under conditions of chronic malnutrition and especially after long-term total parenteral nutrition (TPN). In infants receiving long-term TPN, we observed plasma selenium levels as low as those previously reported in Chinese children with Keshan disease. Low plasma selenium levels were also usually associated with very low activities of glutathione peroxidase. Although clinical symptoms of selenium deficiency did not occur in our patients, several cases have been described in the literature, indicating the need for supplementation in TPN. In order to derive at the appropriate dosage, it is proposed to correlate it with the total protein supply. According to our present knowledge, .5-1.0 micrograms selenium/g of protein appears to be adequate to keep patients in Se balance. For Se repletion of body stores, this dosage has been increased up to 3 micrograms of Se/g of protein. Advantages and disadvantages of selenite and of selenomethionine as possible supplemental forms of Se for TPN solutions are discussed.

References

Jul 1, 1979·JPEN. Journal of Parenteral and Enteral Nutrition·A M van RijC D Thomson
Oct 1, 1979·The American Journal of Clinical Nutrition·A M van RijM F Robinson
Feb 28, 1979·Biochemical and Biophysical Research Communications·F MazeaudA M Michelson
Feb 1, 1978·Toxicology and Applied Pharmacology·S T OmayeC E Cross
Sep 1, 1985·The American Journal of Clinical Nutrition·C D McGeeK N Jeejeebhoy
Aug 1, 1985·Clinics in Endocrinology and Metabolism·J NèveL Molle
Feb 9, 1973·Science·J T RotruckW G Hoekstra
Feb 1, 1983·The American Journal of Clinical Nutrition·C L Kien, H E Ganther
May 1, 1984·The American Journal of Clinical Nutrition·R J BaptistaL Buchanan
May 14, 1981·The New England Journal of Medicine·R A JohnsonH J Cohen
Sep 1, 1982·JPEN. Journal of Parenteral and Enteral Nutrition·H W LaneB S MacFadyen
Jan 1, 1980·Nutrition and Metabolism·S AminS W Klein

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Citations

Jul 15, 1994·Experientia·R S Bedwal, A Bahuguna
Apr 20, 1999·Biological Trace Element Research·R Yanardağ, H Orak
Sep 1, 1996·Biological Trace Element Research·L A Daniels
Aug 1, 1993·Medical Hypotheses·R S BedwalR S Mathur
May 20, 2017·The Cochrane Database of Systematic Reviews·Joshua FeinbergJanus C Jakobsen

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