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Selenium-regulated translation control of heterologous gene expression: normal function of selenocysteine-substituted gene products

Journal of Cellular Biochemistry

Jun 1, 1996

J L LeonardP E Newburger

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Abstract

In eukaryotes, the synthesis of selenoproteins depends on an exogenous supply of selenium, required for synthesis of the novel amino acid, selenocysteine, and on the presence of a "selenium translation element" in the 3' untranslated region of mRNA. The selenium translation element is r...read more

Mentioned in this Paper

Thyroid Hormone Receptor beta-1
Transfection
Ligand Binding
Thyroid Hormone Receptor
Immunocytochemistry
Protein Biosynthesis
Gene Expression
Radioisotopic Labeling (Lab Procedure)
Glutathione peroxidase 1
Cysteine
Paper Details
References
  • References14
  • Citations4
12
  • References14
  • Citations4
1

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Selenium-regulated translation control of heterologous gene expression: normal function of selenocysteine-substituted gene products

Journal of Cellular Biochemistry

Jun 1, 1996

J L LeonardP E Newburger

PMID: 8761945

DOI: 10.1002/(sici)1097-4644(19960601)61:3%3c410::aid-jcb8%3e3.0.co;2-w

Abstract

In eukaryotes, the synthesis of selenoproteins depends on an exogenous supply of selenium, required for synthesis of the novel amino acid, selenocysteine, and on the presence of a "selenium translation element" in the 3' untranslated region of mRNA. The selenium translation element is r...read more

Mentioned in this Paper

Thyroid Hormone Receptor beta-1
Transfection
Ligand Binding
Thyroid Hormone Receptor
Immunocytochemistry
Protein Biosynthesis
Gene Expression
Radioisotopic Labeling (Lab Procedure)
Glutathione peroxidase 1
Cysteine

Feeds With Similar Papers

MicroRNAs & Open Reading Frames

MicroRNAs are small non-coding RNAs that modulate gene expression at post-transcriptional level, playing a crucial role in cell differentiation and development. Discover the latest research on MicroRNAs & how they target Open Reading Frames.

Signal Transduction & Gene Expression (Keystone)

Tumor cells have their own unique signal transduction and gene expression control. Targeting these specific cellular mechanisms and genetic proflies of cancer cells is an area of therapeutic exploration for some cancers. Discover the latest research on this topic with this feed.

Related Papers

Chemical & Pharmaceutical Bulletin

Purification and properties of glutathione peroxidase from human liver

Chemical & Pharmaceutical BulletinJanuary 1, 1983
T MiwaM Sugiura
Paper Details
References
  • References14
  • Citations4
12
  • References14
  • Citations4
1

Download from

Publisher
PubMed
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