Self-assembled micro-organogels for 3D printing silicone structures

Science Advances
Christopher S O'BryanThomas E Angelini

Abstract

The widespread prevalence of commercial products made from microgels illustrates the immense practical value of harnessing the jamming transition; there are countless ways to use soft, solid materials that fluidize and become solid again with small variations in applied stress. The traditional routes of microgel synthesis produce materials that predominantly swell in aqueous solvents or, less often, in aggressive organic solvents, constraining ways that these exceptionally useful materials can be used. For example, aqueous microgels have been used as the foundation of three-dimensional (3D) bioprinting applications, yet the incompatibility of available microgels with nonpolar liquids, such as oils, limits their use in 3D printing with oil-based materials, such as silicone. We present a method to make micro-organogels swollen in mineral oil, using block copolymer self-assembly. The rheological properties of this micro-organogel material can be tuned, leveraging the jamming transition to facilitate its use in 3D printing of silicone structures. We find that the minimum printed feature size can be controlled by the yield stress of the micro-organogel medium, enabling the fabrication of numerous complex silicone structures, includi...Continue Reading

References

Jul 29, 2000·Drug Development and Industrial Pharmacy·A K SinglaA Singh
May 21, 2010·Langmuir : the ACS Journal of Surfaces and Colloids·Jonathan Stringer, Brian Derby
Dec 16, 2011·Nature·Dapeng BiR P Behringer
May 3, 2013·Nano Letters·Manu S MannoorMichael C McAlpine
May 16, 2014·Lab on a Chip·Tim FemmerMatthias Wessling
Aug 6, 2014·Nature Biotechnology·Sean V Murphy, Anthony Atala
Sep 13, 2014·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·E PairamA Fernández-Nieves
Oct 28, 2014·Soft Matter·J A BonhamJ S van Duijneveldt
Apr 14, 2015·Journal of Biological Engineering·Helena N Chia, Benjamin M Wu
Aug 14, 2015·Soft Matter·Robert W StyleEric R Dufresne
Nov 26, 2015·Science Advances·Tapomoy BhattacharjeeThomas E Angelini
Mar 18, 2016·Soft Matter·Charlotte Pellet, Michel Cloitre
Apr 22, 2016·Lab on a Chip·Nirveek BhattacharjeeAlbert Folch
Oct 18, 2016·ACS Biomaterials Science & Engineering·Thomas J HintonAdam W Feinberg
Oct 10, 2016·ACS Biomaterials Science & Engineering·Tapomoy BhattacharjeeThomas E Angelini
Oct 10, 2016·ACS Biomaterials Science & Engineering·Kyle J LeBlancThomas E Angelini

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Citations

Mar 6, 2018·Angewandte Chemie·Longyu LiChenfeng Ke
Mar 25, 2018·Advanced Materials·Joe ForthThomas P Russell
Apr 6, 2018·PloS One·Sara AbdollahiAdam W Feinberg
Nov 8, 2017·Food & Function·Andrew B MathesonPaul S Clegg
Mar 2, 2018·Nature Communications·Manuel SchaffnerAndré R Studart
May 16, 2019·Chemistry : a European Journal·Longyu LiChenfeng Ke
Mar 25, 2019·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Tomohisa YamashitaEtsuko Yunoki
Dec 4, 2019·Advanced Materials·Kony Chatterjee, Tushar K Ghosh
Jan 30, 2020·Macromolecular Rapid Communications·Naser NaserifarGary K Fedder
Aug 20, 2019·Advanced Materials·Elia A Guzzi, Mark W Tibbitt
Jun 18, 2020·Advanced Healthcare Materials·Sara AbdollahiAdam W Feinberg
Jun 27, 2020·Soft Matter·Cameron D MorleyThomas E Angelini
Feb 17, 2018·Soft Matter·Tapomoy BhattacharjeeThomas E Angelini
Jan 16, 2019·Advanced Science·Christopher B HighleyJason A Burdick
Mar 5, 2020·Proceedings of the National Academy of Sciences of the United States of America·Arif Z NelsonPatrick S Doyle
May 5, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Allison L ChauAngela A Pitenis
Jun 22, 2019·Nature Reviews. Materials·Lorenzo MoroniJames J Yoo
Feb 29, 2020·Science Advances·An LiYanlin Song
Oct 31, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jingzhou Zhao, Nongyue He
Jan 10, 2021·Journal of the Mechanical Behavior of Biomedical Materials·James A SmithVadim V Silberschmidt
Jan 22, 2021·ACS Applied Materials & Interfaces·Mohammadreza MahmoudiMajid Minary-Jolandan
Dec 1, 2020·Communications Physics·Bugra AyanIbrahim T Ozbolat
Nov 17, 2020·Biomedical Engineering Letters·Shengyang ChenJuha Song
Feb 11, 2021·APL Bioengineering·Megan E Cooke, Derek H Rosenzweig
Nov 15, 2020·Science Advances·Renxuan XieChristopher M Bates
Mar 9, 2021·Soft Matter·Christopher S O'BryanThomas E Angelini
Mar 2, 2021·APL Bioengineering·Daniel J ShiwarskiAdam W Feinberg
Feb 23, 2021·Advanced Functional Materials·Sarah M HullSarah C Heilshorn
Mar 5, 2019·Acta Biomaterialia·Shen JiMurat Guvendiren
Mar 16, 2021·Additive Manufacturing·Taylor E GreenwoodScott L Thomson
Apr 1, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Arthur CollyEdwin-Joffrey Courtial
Apr 17, 2021·Carbohydrate Polymers·Sungchul Shin, Jinho Hyun
Apr 20, 2021·Journal of Biomechanics·Taylor E Greenwood, Scott L Thomson
Jun 12, 2021·Physical Review Letters·Krutarth KamaniSimon A Rogers
Feb 14, 2020·ACS Applied Materials & Interfaces·Riikka MikkonenMatti Mäntysalo
May 6, 2019·ACS Applied Materials & Interfaces·Jiachen WangDesheng Kong
May 5, 2018·ACS Applied Materials & Interfaces·Christopher P KabbBrent S Sumerlin
Jun 12, 2019·ACS Applied Materials & Interfaces·Lu-Yu ZhouYong He

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Methods Mentioned

BETA
rheology
x-ray scattering
confocal microscopy
Scanning electron microscopy
bioprinting

Software Mentioned

LabVIEW
MATLAB

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