Self-esterification of fulvic acid model compounds in methanolic solvents as observed by electrospray ionization mass spectrometry

Rapid Communications in Mass Spectrometry : RCM
Cameron McIntyreBarry D Batts

Abstract

The self-esterification of two fulvic acid model compounds in methanolic solvents was studied by electrospray ionization mass spectrometry (ESI-MS). The strongly acidic tetrahydrofurantetracarboxylic acid rapidly self-esterified to form mono- and dimethyl esters when stored in methanol, even at reduced temperatures. The weakly acidic analogue, cyclopentanetetracarboxylic acid, reacted minimally under the same conditions. The use of 50:50 methanol/water as a solvent reduced self-esterification of the strong acid. However, the presence of water promoted the formation of multiply charged ions in the ESI mass spectra. The use of water and 50:50 acetonitrile/water as solvents eliminated self-esterification but the mass spectra still contained multiply charged ions. This study implies that the use of methanolic solvents with humic substances may compromise analytical data through the formation of methyl esters.

References

Feb 5, 2000·Analytical Chemistry·T L Brown, J A Rice
Feb 12, 2000·Rapid Communications in Mass Spectrometry : RCM·L PerssonG Odham
May 10, 2001·Rapid Communications in Mass Spectrometry : RCM·G PlancqueC Moulin
Sep 1, 1995·Environmental Science & Technology·F J NovotnyD A Weil

❮ Previous
Next ❯

Citations

Sep 28, 2007·Analytical and Bioanalytical Chemistry·J PeuravuoriK Pihlaja
Aug 14, 2009·Journal of the American Society for Mass Spectrometry·Charly MayeuxJean-François Gal
Jun 7, 2006·Rapid Communications in Mass Spectrometry : RCM·Pierre-Charles MariaMartin Kutsar
Oct 14, 2010·Rapid Communications in Mass Spectrometry : RCM·Antonio NebbiosoMichael Spiteller
Jul 19, 2002·Journal of Mass Spectrometry : JMS
Aug 31, 2002·Rapid Communications in Mass Spectrometry : RCM·Cameron McIntyreBarry D Batts
Apr 12, 2005·Environmental Science & Technology·Pascal ReillerValérie Moulin
May 8, 2020·The Journal of Physical Chemistry. a·Charly MayeuxLionel Massi
Jul 2, 2003·Environmental Science & Technology·Jerry A LeenheerCameron McIntyre

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.