Self-motion perception in Parkinson's disease.

The European Journal of Neuroscience
Orly HalperinAdam Zaidel

Abstract

Parkinson's disease (PD), best characterized by its classic motor symptoms, also manifests non-motor symptoms including perceptual impairments. Normal motor and perceptual brain functions interact continuously in an action-perception loop; hence, perceptual and motor dysfunction in PD are likely also intertwined. A vital skill in order to maintain balance, and to move around in the environment is the ability to perceive one's own motion in space (self-motion perception). Self-motion perception is a complex brain process, that requires the integration of information from visual (optic flow), vestibular (gravito-inertial), and somatosensory senses. Yet, not much is known about self-motion perception or multisensory integration in PD. In this review, we highlight the need to better study these important functions in PD. We review perceptual deficits in underlying functions required for adept self-motion perception (visual, vestibular and somatosensory, as well as multisensory integration) and address how these might affect self-motion perception and motor function in PD. We propose that dysfunction of central brain mechanisms, implicated in impaired visual, vestibular and somatosensory function, likely impact self-motion perceptio...Continue Reading

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Citations

Dec 29, 2020·The European Journal of Neuroscience·Orly HalperinAdam Zaidel
Feb 6, 2021·Brain Sciences·Amit AbrahamGammon M Earhart
Feb 20, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sara Di MarcoSabrina Pitzalis
Mar 25, 2021·The European Journal of Neuroscience·Yoland SmithThomas Boraud

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