Self-ordered pointing and visual conditional associative learning tasks in drug-free schizophrenia spectrum disorder patients.

BMC Psychiatry
Emilio SacchettiStefano Francesco Cappa

Abstract

There is evidence of a link between schizophrenia and a deficit of working memory, but this has been derived from tasks not specifically developed to probe working memory per se. Our aim was to investigate whether working memory deficits may be detected across different paradigms using the self-ordered pointing task (SOPT) and the visual conditional associative learning task (VCALT) in patients with schizophrenia spectrum disorders and healthy controls. The current literature suggests deficits in schizophrenia spectrum disorder patients versus healthy controls but these studies frequently involved small samples, broad diagnostic criteria, inclusion of patients on antipsychotic medications, and were not controlled for symptom domains, severity of the disorder, etc. To overcome some of these limitations, we investigated the self-monitoring and conditional associative learning abilities of a numerically representative sample of healthy controls and a group of non-deteriorated, drug-free patients hospitalized for a schizophrenia spectrum disorder with florid, mainly positive psychotic symptoms. Eighty-five patients with a schizophrenia spectrum disorder (DSM-IV-TR diagnosis of schizophrenia (n = 71) or schizophreniform disorder (n ...Continue Reading

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Citations

Jul 9, 2010·Nursing Ethics·Lora Humphrey Beebe, Kathlene Smith
Feb 14, 2016·Neuropsychological Rehabilitation·Antonio VitaEmilio Sacchetti
Jan 24, 2012·Journal of Psychosocial Nursing and Mental Health Services·Lora H Beebe, Robin Faust Harris
Mar 31, 2010·Journal of Psychosocial Nursing and Mental Health Services·Lora Humphrey BeebeSheila White
Apr 29, 2014·Issues in Mental Health Nursing·Lora BeebeChad Phillips
Mar 6, 2010·Clinical Schizophrenia & Related Psychoses·Lora Humphrey BeebeO Dessieux
Nov 22, 2014·Schizophrenia Research. Cognition·Sohee Park, Diane C Gooding
Jan 3, 2013·International Journal of Mental Health Nursing·Lora Humphrey Beebe, Robin Faust Harris

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Software Mentioned

SOPT
R Language
VCALT

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