PMID: 19113453Dec 31, 2008Paper

Self-organized periodicity of protein clusters in growing bacteria

Physical Review Letters
Hui WangRanjan Mukhopadhyay

Abstract

Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using fluorescence imaging have shown that, during cell growth, lateral clusters form at positions approximately periodically spaced along the cell body. In this Letter, we demonstrate within a lattice model that such spatial organization could arise spontaneously from a stochastic nucleation mechanism. The same mechanism may explain the recent observation of periodic aggregates of misfolded proteins in E. coli.

References

Apr 29, 1999·Proceedings of the National Academy of Sciences of the United States of America·D M Raskin, P A de Boer
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·T A Duke, D Bray
Feb 4, 2003·Journal of Bacteriology·Lee Kroos, Janine R Maddock
Oct 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Kerwyn Casey HuangNed S Wingreen
Jan 13, 2004·Proceedings of the National Academy of Sciences of the United States of America·Anuradha Janakiraman, Marcia B Goldberg
Mar 5, 2004·European Biophysics Journal : EBJ·Jacki GoldmanDennis Bray
Mar 26, 2004·Nature·Victor Sourjik, Howard C Berg
Oct 19, 2005·Proceedings of the National Academy of Sciences of the United States of America·Claudia A Studdert, John S Parkinson
Aug 12, 2006·Science·Eric BetzigHarald F Hess
Mar 3, 2007·The EMBO Journal·Sebastian ThiemVictor Sourjik
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Peijun ZhangSriram Subramaniam
Feb 22, 2008·Proceedings of the National Academy of Sciences of the United States of America·Ariel B LindnerFrançois Taddei
Apr 23, 2008·Proceedings of the National Academy of Sciences of the United States of America·Sonja SchulmeisterVictor Sourjik
May 15, 2008·Molecular Microbiology·Sebastian Thiem, Victor Sourjik

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Citations

Aug 25, 2011·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Greg HuberRanjan Mukhopadhyay
May 11, 2010·Cold Spring Harbor Perspectives in Biology·David Z Rudner, Richard Losick
Nov 19, 2010·PLoS Computational Biology·Saeed Saberi, Eldon Emberly
May 24, 2013·PloS One·Saeed Saberi, Eldon Emberly
Jan 1, 2014·Proceedings of the National Academy of Sciences of the United States of America·Simon RinggaardMatthew K Waldor
Jun 10, 2010·Annual Review of Microbiology·David Kentner, Victor Sourjik
Dec 19, 2013·Journal of Cell Science·Géraldine Laloux, Christine Jacobs-Wagner
Jan 6, 2011·Molecular Systems Biology·Barbara Di Ventura, Victor Sourjik
Aug 16, 2013·Molecular Microbiology·Sheng-Wen ChiuJudith P Armitage
Aug 19, 2010·The EMBO Journal·Victor Sourjik, Judith P Armitage
Nov 30, 2012·Molecular Microbiology·Sarah B GuttenplanDaniel B Kearns
Apr 12, 2014·Molecular Microbiology·Thiago M A SantosDouglas B Weibel
Apr 7, 2015·Trends in Microbiology·Christopher W Jones, Judith P Armitage
Aug 26, 2014·Frontiers in Microbiology·Karlton ScheuEldon Emberly
Dec 17, 2014·PLoS Computational Biology·Christoph A Haselwandter, Ned S Wingreen
Oct 22, 2015·Annual Review of Microbiology·Ned S Wingreen, Kerwyn Casey Huang
Jan 1, 2017·New Journal of Physics·Vaibhav WasnikRanjan Mukhopadhyay
Nov 3, 2015·Nature Communications·H StrahlL W Hamoen
Apr 19, 2019·Scientific Reports·Aleksandra A FilkovaAnastasia N Sveshnikova
Sep 15, 2015·PLoS Computational Biology·Alexander UllrichFrank Noé
Aug 3, 2019·The Journal of General Physiology·Daisuke SatoL Fernando Santana
Oct 27, 2018·Nature Communications·Moriah KolerAdy Vaknin
Feb 14, 2015·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Mahdi Rezaei KeramatiEldon Emberly
Jun 15, 2017·Frontiers in Cellular and Infection Microbiology·Sachith D GunasingheTrevor Lithgow
Mar 17, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Ksenia GusevaAlessandro de Moura
Feb 5, 2010·Journal of Cell Science·Marek CebecauerAnthony I Magee

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