Self-Regulated Dynamical Criticality in Human ECoG

Frontiers in Integrative Neuroscience
Guillermo SoloveyGuillermo A Cecchi


Mounting experimental and theoretical results indicate that neural systems are poised near a critical state. In human subjects, however, most evidence comes from functional MRI studies, an indirect measurement of neuronal activity with poor temporal resolution. Electrocorticography (ECoG) provides a unique window into human brain activity: each electrode records, with high temporal resolution, the activity resulting from the sum of the local field potentials of ∼10(5) neurons. We show that the human brain ECoG recordings display features of self-regulated dynamical criticality: dynamical modes of activation drift around the critical stability threshold, moving in and out of the unstable region and equilibrating the global dynamical state at a very fast time scale. Moreover, the analysis also reveals differences between the resting state and a motor task, associated with increased stability of a fraction of the dynamical modes.

Associated Proceedings Papers

Jul 10, 2017·Arian AshourvanGeorge J. Pappas
Sep 4, 2019·A. L. RiveraJ. C. Toledo-Roy


Apr 6, 2016·Frontiers in Neural Circuits·Tiago L RibeiroMauro Copelli
Feb 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·J Matias PalvaSatu Palva
Apr 12, 2014·Frontiers in Neural Circuits·Leandro M AlonsoMarcelo O Magnasco
May 25, 2016·Neuroscience and Biobehavioral Reviews·D P CalderonD Pfaff
May 5, 2017·PloS One·Leila FakhraeiWoodrow L Shew
Dec 8, 2017·Reports on Progress in Physics·William Bialek
Jun 21, 2018·Journal of Neural Engineering·Mackenna HillCynthia A Chestek
Jan 19, 2019·Proceedings of the National Academy of Sciences of the United States of America·Antonio C CostaGreg J Stephens
Aug 9, 2013·Journal of Neurophysiology·Greg J StephensUri Hasson
Mar 13, 2015·Physical Review Letters·Thierry MoraOlivier Marre
Jun 14, 2019·Proceedings of the National Academy of Sciences of the United States of America·David DahmenMoritz Helias
Jan 24, 2015·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Rashid V Williams-GarcíaGerardo Ortiz

Related Concepts

Specimen Type - Electrode
Interphase Cell
Eastern Cooperative Oncology Group Performance Status Questionnaire

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Related Papers

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
C J Stam
PLoS Computational Biology
Manfred G KitzbichlerEd Bullmore
Frontiers in Physiology
John M Beggs, Nicholas Timme
© 2020 Meta ULC. All rights reserved