Self-reported treatment adherence in inflammatory bowel disease in Indian patients.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
Jay BhattDevendra Desai

Abstract

Non-adherence to medical therapy is emerging as an important determinant of relapse in patients with inflammatory bowel disease (IBD). To find the prevalence of and reasons for nonadherence to medical therapy in Indian patients with IBD and its correlation with disease outcome. In this cross-sectional study, we checked for adherence to treatment in 127 patients with IBD (117 ulcerative colitis and 10 Crohn's disease) using a questionnaire that inquired into frequency of missed doses, causes for missed doses, and its relation to relapse of disease. Of the 127 patients (mean age 42.8 years; 68 women), 103 (81%) were non-adherent to treatment, defined as taking 80% or less of the dose advised. The reasons for non-adherence (not mutually exclusive) were: forgetfulness-98 patients (77%), felt better-18 (14.2 %), high frequency of doses-13 (10.1%), no effect of medications-10 (7.87%), non-availability of medications-3 (2.3%). Non-adherent patients were three times more likely to develop a relapse as compared to those with adherence (OR 3.389, 95% CI 1.29-8.88, p=0.012). Over 80% of patients with IBD in this survey were non-adherent to medical treatment; forgetfulness was mentioned as the most common cause. Non-adherent patients were ...Continue Reading

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Citations

Oct 18, 2012·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Govind K MakhariaUNKNOWN Indian Society of Gastroenterology Task Force on Inflammatory Bowel Disease
Oct 26, 2012·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Balakrishnan S RamakrishnaUNKNOWN Indian Society of Gastroenterology Task Force on Inflammatory Bowel Diseases
Aug 17, 2012·BMC Gastroenterology·Stefan SchreiberKristine Paridaens
Mar 13, 2014·Scandinavian Journal of Gastroenterology·Valérie PittetUNKNOWN Swiss IBD Cohort Study Group
May 10, 2011·Expert Opinion on Drug Safety·Christian P SelingerRupert W Leong
Nov 3, 2016·Expert Review of Gastroenterology & Hepatology·Cristina BezzioSimone Saibeni
Jun 4, 2011·The American Journal of Gastroenterology·Anne C TravisArvey I Rogers
Jun 15, 2017·World Journal of Gastroenterology : WJG·Anita Afzali, Ghassan Wahbeh
Jan 29, 2020·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Simon R Knowles, George Alex
Aug 14, 2019·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Sanjeevani K TomarVineet Ahuja
Oct 9, 2020·BioMed Research International·Laíla D AndradeGenoile O Santana
Dec 4, 2020·World Journal of Gastroenterology : WJG·Ruma RajbhandariGene Bukhman

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