Semantic activation and implicit memory in Alzheimer disease

Alzheimer Disease and Associated Disorders
J BrandtM Folstein

Abstract

Patients with Alzheimer disease (AD) invariably display pronounced deficits in verbal memory when retention is tested explicitly. The present study examined the possibility that tasks which require memory only implicitly would be performed normally. Moderately demented patients with probable AD were severely impaired in free recall of a word list. On a subsequent word association test, the AD patients were less likely than normals to give items from the recall list as their word associations. The results suggest that implicit verbal memory, as well as explicit memory, is impaired in AD. While the magnitude of the activation effect was significantly reduced in AD patients, it was uncorrelated with recall performance or a measure of global cognitive functioning. Memory activation may thus depend on neural circuitry outside the traditional (i.e. temporo-limbic) memory system.

Citations

Jun 1, 1992·Neuropsychology Review·G A Carlesimo, M Oscar-Berman
Nov 5, 1997·Neuropsychologia·W C HeindelD P Salmon
May 17, 2005·Journal of the International Neuropsychological Society : JINS·Kirsten I TaylorPeter Brugger
Apr 1, 1990·The Journal of General Psychology·R E Landrum, R C Radtke
Jul 1, 1992·Journal of Clinical and Experimental Neuropsychology·D FriedmanK Marder
Sep 1, 1992·Journal of Clinical and Experimental Neuropsychology·J BrandtL Krafft
Dec 1, 1994·Journal of Clinical and Experimental Neuropsychology·B LipinskaM Viitanen
Nov 15, 2011·Applied Neuropsychology·Anya Mazur-MosiewiczRaymond S Dean
Nov 6, 2009·Journal of Clinical and Experimental Neuropsychology·Xavier MilletHélène Amieva
Jun 1, 1990·Psychological Reports·F EustacheL Pons
Jul 10, 2001·Aging : Clinical and Experimental Research·F Boller, G D Barba
Dec 1, 1995·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·A M ErgisB Deweer
Jul 21, 1998·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·A M ErgisB Deweer
Oct 27, 1997·Brain and Cognition·D A FleischmanJ D Gabrieli
May 11, 2010·Social Science & Medicine·Sarah L SzantonKeith Whitfield
Sep 6, 2017·American Journal of Alzheimer's Disease and Other Dementias·Siran M KoroukianKathleen A Smyth
Oct 6, 2009·Current Protocols in Neuroscience·Sharelle Baldwin, Sarah Tomaszewski Farias
Jun 25, 2005·Brain : a Journal of Neurology·Debra A FleischmanDavid A Bennett

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.