Semi-automated screening of biomedical citations for systematic reviews.

BMC Bioinformatics
Byron C WallaceChristopher H Schmid

Abstract

Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and critical step in systematic reviews. Typically, reviewers must evaluate thousands of citations to identify articles eligible for a given review. We explore the application of machine learning techniques to semi-automate citation screening, thereby reducing the reviewers' workload. We present a novel online classification strategy for citation screening to automatically discriminate "relevant" from "irrelevant" citations. We use an ensemble of Support Vector Machines (SVMs) built over different feature-spaces (e.g., abstract and title text), and trained interactively by the reviewer(s). Semi-automating the citation screening process is difficult because any such strategy must identify all citations eligible for the systematic review. This requirement is made harder still due to class imbalance; there are far fewer "relevant" than "irrelevant" citations for any given systematic review. To address these challenges we employ a custom active-learning strategy developed specifically for imbalanced datasets. Further, we introduce a novel undersampling technique. We provide e...Continue Reading

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Citations

Apr 7, 2012·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Byron C WallaceThomas A Trikalinos
Feb 1, 2013·Journal of the American Medical Informatics Association : JAMIA·Yukun ChenHua Xu
Feb 22, 2014·PLoS Medicine·Julian H ElliottRussell L Gruen
Feb 23, 2013·International Journal of Computational Biology and Drug Design·Siddhartha Jonnalagadda, Diana Petitti
Mar 26, 2013·Clinical Epidemiology·Farrah J MateenBiren B Kamdar
Nov 19, 2013·Journal of Comparative Effectiveness Research·Byron C WallaceThomas A Trikalinos
Jun 21, 2014·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Rebecca PerssonKatrin Uhlig
Dec 4, 2013·Journal of Minimally Invasive Gynecology·Rajiv B GalaUNKNOWN Society of Gynecologic Surgeons Systematic Review Group
Jun 9, 2012·Artificial Intelligence in Medicine·Tanja Bekhuis, Dina Demner-Fushman
Nov 22, 2014·Obstetrics and Gynecology·David D RahnUNKNOWN Society of Gynecologic Surgeons Systematic Review Group
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Mar 24, 2016·Journal of Biomedical Informatics·Zhiguo YuTodd R Johnson
Nov 28, 2015·Systematic Reviews·Yuanhan MoSophia Ananiadou
Nov 14, 2015·Systematic Reviews·Alexander TsertsvadzeNoel McCarthy
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Jun 14, 2016·Journal of Biomedical Informatics·Kazuma HashimotoSophia Ananiadou
Jul 10, 2014·Systematic Reviews·Guy TsafnatEnrico Coiera
Apr 7, 2017·Obstetrics and Gynecology·Peter C JeppsonUNKNOWN Society of Gynecologic Surgeons Systematic Review Group
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Sep 2, 2020·Journal of the American College of Nutrition·Kristin M NiemanChristopher J Cifelli

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Software Mentioned

Patient Active
MetaMap
LibSVM
SIMPLE

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