Nov 6, 2008

Semi-automatic reference standard construction for quantitative evaluation of lung CT registration

Medical Image Computing and Computer-assisted Intervention : MICCAI
K MurphyM Staring

Abstract

An algorithm is presented for the efficient semi-automatic construction of a detailed reference standard for registration in thoracic CT. A well-distributed set of 100 landmarks is detected fully automatically in one scan of a pair to be registered. Using a custom-designed interface, observers locate corresponding anatomic locations in the second scan. The manual annotations are used to learn the relationship between the scans and after approximately twenty manual marks the remaining points are matched automatically. Inter-observer differences demonstrate the accuracy of the matching and the applicability of the reference standard is demonstrated on two different sets of registration results over 19 CT scan pairs.

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Mentioned in this Paper

CT of Lungs
Lung
Subtraction Technique
X-Ray Computed Tomography
Dissecting Aneurysm of the Thoracic Aorta
Chest
Tomography, X-Ray Computerized Axial
Radiographic Image Interpretation, Computer-Assisted
Digital Radiography
Malignant Neoplasm of Lung

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