Semiautomatic evaluation of left ventricular diastolic function with cine magnetic resonance imaging

Academic Radiology
F L HoffP R Liebson

Abstract

Cine magnetic resonance (MR) imaging is a relatively new technique that can be used to study cardiac function with high spatial and temporal resolution. However, detailed functional analysis of the entire cardiac cycle with cine MR imaging is time consuming and labor intensive. We analyzed diastolic function using a semiautomatic routine that reduces the time necessary for analysis. Twenty subjects (10 normal control subjects and 10 patients with isolated diastolic dysfunction) were examined. Short-axis cine MR images were obtained at 32 phases of the cardiac cycle. A semiautomatic boundary-finding routine was used to determine left ventricular (LV) volumes at each phase. Volume-versus-time and first-derivative curves were created from these data. Several parameters derived from the MR imaging curves were used to characterize diastole. Two parameters--the ratio of early peak filling rate to late peak filling rate and the percentage of filling during early diastole--perfectly distinguished subjects with LV diastolic dysfunction from the normal control subjects. The semiautomatic analysis method substantially reduced the time necessary for analyzing the MR imaging data, compared with manual analysis. Cine MR imaging, especially w...Continue Reading

Citations

Sep 26, 2008·Current Treatment Options in Cardiovascular Medicine·Pamela K WoodardGautam K Singh
Nov 11, 2010·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Emilie BollacheNadjia Kachenoura
Jan 25, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jérôme CaudronJean-Nicolas Dacher
Jul 16, 2013·Journal of the Mechanical Behavior of Biomedical Materials·M Jamshidi, M T Ahmadian
Dec 11, 2007·Journal of Theoretical Biology·D-E Bettendorff-BakmanP Niederer
Dec 25, 2010·Clinical Cardiology·Brett M Victor, John T Barron
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Mar 28, 2006·Seminars in Ultrasound, CT, and MR·Pamela K WoodardFernando R Gutierrez
Jul 9, 2005·Journal of Theoretical Biology·D-E Bettendorff-BakmanP Niederer
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