PMID: 107453Jan 1, 1978

Semiessential and nonessential amino acids in parenteral feeding

Die Nahrung
J N KremerA A Schmidt

Abstract

With reference to a critical study of the relevant literature and to results from their own investigations, the authors emphasize the importance of the semi-essential and non-essential amino acids arginine, histidine, tyrosine, cystine and glutamic acid for the completion of essential amino-acid mixtures destined for parenteral feeding. MADDEN'S assumption that intravenously applied glutamic acid is intolerable was not supported by the authors' experiments in dogs. As evidenced by the increase of blood urea, the glutamic acid-containing amino-acid mixture was well utilizable. When glutamic acid is present, proline and alanine are obviously superfluous in amino-acid mixtures for parenteral feeding, since they are easily formed from glutamic acid by intermediary metabolism.

References

Aug 1, 1973·The American Journal of Clinical Nutrition·C P WenS N Gershoff
Feb 1, 1973·Metabolism: Clinical and Experimental·P Felig
May 1, 1973·Journal of Biochemistry·T Yoshida, G Kikuchi
Jul 1, 1970·Physiological Reviews·A E HarperR M Wohlhueter
Apr 12, 1965·Biochimica Et Biophysica Acta·K L MANCHESTER

Related Concepts

Amino Acids, Essential
Arginine hydrochloride
Copper Cystinate
Food, Formulated
Glutamic Acids
Histidine
Dietary Requirements
Parenteral Nutrition
Tyrosine

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