Seminal prostaglandins in infertile men.

Fertility and Sterility
J G CollierS L Stanton

Abstract

The concentration of prostaglandin E (PGE) was measured in the semen of 5 men of proven fertility and in 12 men of couples who were infertile but in whom no abnormality had been detected by conventional semen analysis, postcoital test of sperm motility, endometrial biopsy, and laparoscopic dye insufflation of the fallopian tubes. In the fertile men the mean PGE concentration was 52.7 +/- 9.9 mug/ml, and in infertile men the concentration was 22.1 +/- 2.76 mug/ml; the difference between the two groups was highly significant (P less than 0.001). In five of the infertile men attempts were made to raise the PGE concentration by the administration of either corn oil, which contains the prostaglandin precursor linoleic acid, or caffeine, which inhibits prostaglandin degradation; the response to both agents was insignificant.

Citations

Jan 1, 1985·The Veterinary Quarterly·A J Higgins
Mar 1, 1980·Andrologia·A K Didolkar, D Roychowdhury
Mar 16, 2006·The Journal of Toxicological Sciences·Tze-Kiong ErJau-Nan Lee
Apr 1, 1987·International Journal of Andrology·E BendvoldP Eneroth
Jan 1, 1981·Prostaglandins·W SchlegelE Nieschlag

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.