Semiological and electroencephalographic features of epilepsy with amygdalar lesion

Epilepsy Research
XiaoPing DuYushi Inoue

Abstract

To identify semiological and scalp/sphenoidal electroencephalographic (EEG) features of epilepsy with amygdalar lesion (AL). This study included 17 patients with epilepsy and distinct AL on MRI, who underwent resective surgery. There were nine female and eight male patients with ages at surgery ranging from 8 to 48 (mean 26.3) years. Postoperative seizure outcome was Engel class I or seizure-free in 12 patients, class II in four, and class III in one. Pathological examination revealed dysembryoplastic neuroepithelial tumor in eight cases, astrocytoma in two, mixed oligoastrocytoma in three, ganglioglioma in two, localized encephalitis in one, and cortical dysplasia in one. Semiology and scalp/sphenoidal EEG findings of these patients (AL group) were compared with those of 20 mesial temporal lobe epilepsy patients with hippocampal sclerosis (HS) who underwent resective surgery with favorable seizure outcome (Engel class I) (control group). Increased tonic components during seizure were more frequently seen in AL group (58.8%) than in control group (20%). Interictal unitemporal slow waves were more frequently found in AL group (58.8%) than in control group (20%). Ictal EEG revealed generalized (not only bitemporal) onset in six p...Continue Reading

References

Sep 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·L A MillerD G Munoz
Sep 1, 1993·Epilepsia·E WyllieH Lüders
Jul 23, 1998·Neurology·V AcharyaH Lüders
Sep 17, 1998·Epilepsia·H LüdersE Wyllie
Sep 21, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G AvanziniM de Curtis
Feb 1, 2003·Epilepsia·Chien ChenChun-Hing Yiu
Aug 23, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·S P C BowerM J Cook
Jun 5, 2007·Trends in Neurosciences·John R Huguenard, David A McCormick
Apr 27, 2012·Epilepsia·Giuliano AvanziniGiuseppe Capovilla

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Citations

Feb 12, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hsiang-Yu YuChien Chen
Aug 19, 2021·Practical Neurology·Fahmida A ChowdhuryMatthew C Walker

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