Semiparametric regression splines in matched case-control studies

Biometrics
Inyoung KimRaymond J Carroll

Abstract

We develop semiparametric methods for matched case-control studies using regression splines. Three methods are developed: 1) an approximate cross-validation scheme to estimate the smoothing parameter inherent in regression splines, as well as 2) Monte Carlo expectation maximization (MCEM) and 3) Bayesian methods to fit the regression spline model. We compare the approximate cross-validation approach, MCEM, and Bayesian approaches using simulation, showing that they appear approximately equally efficient; the approximate cross-validation method is computationally the most convenient. An example from equine epidemiology that motivated the work is used to demonstrate our approaches.

References

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Citations

Oct 3, 2008·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Silke StrackeHans-Peter Piepho
May 9, 2012·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·J M González-CamachoJ Crossa
Aug 21, 2012·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Torben Schulz-StreeckHans-Peter Piepho
Mar 6, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S Ullah, C F Finch
Nov 17, 2010·Cancer Causes & Control : CCC·Sara E WagnerJames R Hébert
Sep 11, 2008·Journal of Pharmacokinetics and Pharmacodynamics·Yi WangShunpu Zhang
Nov 8, 2008·Journal of Pharmacokinetics and Pharmacodynamics·Yi WangDong Wang
Nov 30, 2013·Population Research and Policy Review·Bethany G EverettRichard G Rogers
Oct 5, 2013·Psychometrika·Xin-Yuan SongEdward Hak-Sing Ip
Sep 11, 2014·Psychometrika·Gerhard Tutz, Jan Gertheiss
Jul 11, 2009·Environmental Health Perspectives·Christopher J Paciorek, Yang Liu
Dec 24, 2013·Journal of the American Statistical Association·Xiaolei XunArnab Maity
Jun 23, 2019·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yinan HuSarah McMenamin
Jan 1, 2009·Electronic Journal of Statistics·David RuppertRaymond J Carroll

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