Senile Lemierre syndrome complicated with descending necrotizing mediastinitis: A case report

Medicine
Xu YangZhao-Yao Sun

Abstract

Senile patients with LS complicated with DNM are rarely seen in clinical practice, and extensive cervical incision and drainage plus administration of effective antibiotics are the basis for treatment. Currently, the treatment controversy mainly has focused on whether mediastinal incision and drainage is necessary for patients with type I DNM, and whether anticoagulation therapy is required for jugular venous emboli and distant metastatic emboli induced by LS. A female, 76 years old, developed pain of tonsil on right side 5 days ago, and felt that the pain aggravated complicated with dysphagia and swelling pain of neck on both sides since then. She was diagnosed with LS complicated with type I DNM. Tazobactam and Piperacillin 4.5 q8h and Ornidazole 100 ml q6h ivgtt were administered empirically,and secondary extensive cervical incision and drainage was performed under general anesthesia, after which low molecular weight heparin 4250 U q12h SC was administered. G test was performed 3 days later, which showed (1,3)-β-D-glucan >1000 pg/ml. Bridging anticoagulation therapy, low molecular weight heparin 4250 U q12h SC, and Warfarin 2.5 mg qd po were given one week later. Low molecular weight heparin SC was discontinued and only Warf...Continue Reading

References

Mar 17, 1999·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·S EndoH Nishino
Apr 13, 2000·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·H SakamotoJ Sasaki
Apr 28, 2004·The Annals of Thoracic Surgery·Noritaka IsowaKoji Chihara
Aug 11, 2004·International Journal of Pediatric Otorhinolaryngology·Waheeb SakranRaul Colodner
Aug 28, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Fabio RocciaSid Berrone
Jul 8, 2008·The Journal of Thoracic and Cardiovascular Surgery·Ke-Cheng ChenYung-Chie Lee
Apr 21, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K EinhäuplUNKNOWN European Federation of Neurological Societies
Aug 9, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Thomas SarnaAntonia Kolokythas
May 9, 2012·Southern Medical Journal·William F WrightJulie A Ribes
Aug 18, 2012·International Journal of Clinical Pharmacy·Thuyvan Phan, Tsz-Yin So
Mar 17, 2016·Annals of Maxillofacial Surgery·Dani NoyOmri Emodi
Aug 9, 2016·International Journal of Pediatric Otorhinolaryngology·Jenna RebeloDoron D Sommer
Dec 23, 2016·Acta Haematologica·Margaret C Cupit-LinkVilmarie Rodriguez
Feb 6, 2017·General Thoracic and Cardiovascular Surgery·Taisuke KaihoIchiro Yoshino
Jun 6, 2017·Intractable & Rare Diseases Research·Adam AlpersteinSalman Muddassir
Jun 27, 2017·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Karl CuddyAshish Patel

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