Sensations evoked by microstimulation of single mechanoreceptive afferents innervating the human face and mouth

Journal of Neurophysiology
M Trulsson, G K Essick

Abstract

Intraneural microneurography and microstimulation were performed on single afferent axons in the inferior alveolar and lingual nerves innervating the face, teeth, labial, or oral mucosa. Using natural mechanical stimuli, 35 single mechanoreceptive afferents were characterized with respect to unit type [fast adapting type I (FA I), FA hair, slowly adapting type I and II (SA I and SA II), periodontal, and deep tongue units] as well as size and shape of the receptive field. All afferents were subsequently microstimulated with pulse trains at 30 Hz lasting 1.0 s. Afferents recordings whose were stable thereafter were also tested with single pulses and pulse trains at 5 and 60 Hz. The results revealed that electrical stimulation of single FA I, FA hair, and SA I afferents from the orofacial region can evoke a percept that is spatially matched to the afferent's receptive field and consistent with the afferent's response properties as observed on natural mechanical stimulation. Stimulation of FA afferents typically evoked sensations that were vibratory in nature; whereas those of SA I afferents were felt as constant pressure. These afferents terminate superficially in the orofacial tissues and seem to have a particularly powerful acce...Continue Reading

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Citations

Oct 22, 2010·Experimental Brain Research·M BjörnsdotterH Olausson
Aug 8, 1998·Journal of Neuroscience Methods·J ZygierewiczS E Folger
Sep 13, 2013·Proceedings. Biological Sciences·Nobuhiro HaguraPatrick Haggard
Oct 7, 2014·Neuroscience and Biobehavioral Reviews·Patrick Haggard, Lieke de Boer
Feb 7, 2015·Clinical Oral Implants Research·Joannis GrigoriadisKrister G Svensson
Apr 12, 2016·Journal of Oral Rehabilitation·L J Pereira, A van der Bilt
Jun 9, 2016·Interface Focus·Peter W LucasAnthony G Atkins
Apr 16, 2013·Pain·Miyuki FukuokaAkihiko Ikoma
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Nov 22, 2011·Nature Neuroscience·Matthias HeidenreichGary R Lewin
Jul 30, 2010·Journal of Neurophysiology·Mats TrulssonFrancis McGlone
Jul 4, 2020·Attention, Perception & Psychophysics·Matthew R LongoElena Azañón
Sep 24, 2020·Journal of Neurophysiology·Giulia Corniani, Hannes P Saal
Apr 1, 2021·The Journal of Comparative Neurology·Yalda MoayediEllen A Lumpkin
Jun 3, 2021·International Journal of Molecular Sciences·Man-Kyo ChungYu Shin Kim

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