Sensing capabilities of colloidal gold modified with a self-assembled monolayer of a glucose-carrying polymer chain on a glass substrate

Langmuir : the ACS Journal of Surfaces and Colloids
Shinta MorokoshiHiromi Kitano

Abstract

A disulfide-carrying polymer with pendent glucose residues (poly(2-methacryloyloxyethyl D-glucopyranoside)) was obtained by using a benzyl N,N-diethyldithiocarbamoyl derivative which shows the abilities of initiation, chain transfer, and termination (iniferter). The disulfide-carrying polymer was accumulated on a colloidal Au-immobilized glass substrate, and the usefulness of the polymer as a sensing element of concanavalin A (Con A) was examined by using a UV-visible spectrophotometer with the help of surface plasmon resonance. The sensor showed a concentration-dependent specific binding of Con A with a detection limit of 1.9 nM, and furthermore, it had a very high stability at high ionic strength. The polymer-coated device examined here was not only useful as a simple biosensor chip but is also expected to expand our knowledge of interfacial phenomena by introducing various functional polymers on colloidal Au.

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Citations

Oct 13, 2006·Chemical Communications : Chem Comm·Sebastian G SpainNeil R Cameron
Feb 22, 2012·Colloids and Surfaces. B, Biointerfaces·Hisatomo SuzukiYoshiyuki Saruwatari
Aug 9, 2011·Colloids and Surfaces. B, Biointerfaces·Hiromi KitanoKohji Ohno
Mar 27, 2010·Colloids and Surfaces. B, Biointerfaces·Hiromi KitanoNaoki Kanayama
Oct 21, 2015·Biotechnology Advances·Ali K YetisenSeok Hyun Yun
Dec 23, 2008·Journal of Colloid and Interface Science·Hiromi KitanoKazuhiro Matsuura
Feb 20, 2007·Colloids and Surfaces. B, Biointerfaces·Yasutaka AnrakuMami Hakari
Dec 14, 2004·Journal of Colloid and Interface Science·Hiromi KitanoShinta Morokoshi
Oct 7, 2004·Journal of Colloid and Interface Science·Hiromi KitanoHideaki Kawasaki
Sep 12, 2006·Colloids and Surfaces. B, Biointerfaces·Hiromi KitanoYoshiyuki Saruwatari
Apr 12, 2016·Journal of Biomedical Materials Research. Part a·Miku NishidaYoshiyuki Saruwatari
Oct 29, 2015·Chemical Reviews·Yoshiko MiuraHirokazu Seto
Aug 31, 2017·Nanotechnology·Noboru SaitoKaoru Tamada
Jun 13, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Hiromi KitanoYoshiyuki Saruwatari
Jun 9, 2011·Chemical Reviews·Kathryn M Mayer, Jason H Hafner
Mar 23, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Abdelghani HousniRavin Narain
Aug 9, 2005·Environmental Science & Technology·Tadashi Nakaji-HirabayashiHiromi Kitano
Feb 9, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Hiroshi EndoHiromi Kitano

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