Sensitivity and Specificity of 50% Excess Weight Loss (50%EWL) and Twelve Other Bariatric Criteria for Weight Loss Success

Obesity Surgery
Arnold W van de LaarS C Bruin

Abstract

Criteria for bariatric weight loss success are numerous. Most of them are arbitrary. None of them is evidence-based. Our objective was to determine their sensitivity and specificity. Thirteen common bariatric weight loss criteria were compared to a benchmark reflecting the gold standard in bariatric surgery. We used an elaborate baseline BMI-independent weight loss percentile chart, based on retrospective data after laparoscopic Roux-en-Y gastric bypass (LRYGB), performed between 2007 and 2017. Percentile curves p31.6 (patients' expectation), p25 (interquartile range), p15.9 (1 standard deviation (SD) below median), and p10.9 (surgeons' goal) were used as possible cutoff for success to determine true or false positive and negative results beyond 1 year. We operated 4497 primary LRYGB patients, with mean follow-up 22 (± 1 SD 19; range 0-109) months, 3031 patients with last result ≥ 1 year, 518 ≥ 5 years. For all four cutoff percentile curves for success, specificities were low (2-72%) for criteria < 35 body mass index (BMI), ≥ 25percentage excess BMI loss (%EBMIL), ≥ 50%EBMIL, ≥ 15 percentage total weight loss (%TWL), ≥ 20%TWL, ≥ 25 percentage excess weight loss (%EWL), and high (83-96%) for < 30 BMI. No criterion had > 80% spec...Continue Reading

References

Jul 31, 2007·Obesity Surgery·Mervyn DeitelJohn Melissas
Aug 24, 2007·The New England Journal of Medicine·Lars SjöströmUNKNOWN Swedish Obese Subjects Study
Mar 11, 2009·The American Journal of Medicine·Henry BuchwaldIsabella Sledge
Mar 12, 2009·Obesity Surgery·Ramsey M DallalLeonard E Braitman
Mar 25, 2009·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Ronette L KolotkinTed D Adams
Aug 5, 2010·Obesity Surgery·Aniceto BaltasarFernando Borrás
Aug 13, 2011·Obesity Surgery·Masha LivhitsMelinda Maggard Gibbons
Aug 28, 2012·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Alessandro MorAlfonso Torquati
Oct 15, 2013·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Arnold W J M van de Laar
Dec 10, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Jérémie ThereauxJean-Luc Bouillot
Dec 18, 2014·Obesity Surgery·Jake P MannJulian H Barth
Mar 25, 2015·Obesity Surgery·Stacy A BrethauerUNKNOWN ASMBS Clinical Issues Committee
Jul 16, 2015·Diabetes Technology & Therapeutics·Ali AminianStacy A Brethauer
Oct 20, 2015·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·A W van de LaarE W Meesters
Jan 25, 2016·Obesity Surgery·Ricard CorcellesPhilip R Schauer
Oct 21, 2016·Obesity Surgery·Alicia Molina LópezDaniel Del Castillo Déjardin
Aug 19, 2016·Psychological Assessment·Ryan J MarekKathleen Ashton
Jan 11, 2017·Journal of Diabetes·Payal H MaratheKelly L Close

❮ Previous
Next ❯

Citations

Nov 5, 2019·Obesity Surgery·Vera VoorwindeMaartje M van Stralen
Jan 1, 2020·Annals of the Royal College of Surgeons of England·N SamuelS Balachandra
Aug 26, 2020·Journal of Endocrinological Investigation·C D'EusebioS Bo
Dec 16, 2018·Obesity Surgery·Chetan D ParmarK K Mahawar
Sep 29, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Yinfang TuHaoyong Yu
Dec 4, 2019·Annals of Gastroenterological Surgery·Atsuhito SaikiUNKNOWN Japanese Survey of Morbid and Treatment‐Resistant Obesity Group (J‐SMART Group)
Mar 22, 2021·The Surgical Clinics of North America·Kevin Climaco, Eric Ahnfeldt
Nov 7, 2020·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Arnold W J M van de LaarMax Nieuwdorp
Jun 20, 2021·Obesity Surgery·Macarena Torrego-EllacuríaMiguel Angel Rubio
Sep 15, 2021·Diabetes Care·Douglas BartholdKaren J Coleman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.