PMID: 7580708Oct 28, 1995Paper

Sensitivity and specificity of photography and direct ophthalmoscopy in screening for sight threatening eye disease: the Liverpool Diabetic Eye Study

BMJ : British Medical Journal
S P HardingJ Vora

Abstract

To evaluate different methods for community based screening for sight threatening diabetic eye disease. Prospective study. Mobile screening unit visiting inner city community clinics; hospital assessment clinic (tertiary centre). 395 diabetic patients registered with four general practices in an inner city location. Community based photography with mydriasis and direct ophthalmoscopy through dilated pupils by an experienced ophthalmologist, both compared with reference standard of slit lamp biomicroscopy by a consultant specialist in medical retinal disease. Sensitivity and specificity of screening method and prevalence of sight threatening diabetic eye disease (moderate preproliferative retinopathy, circinate maculopathy, exudate within 1 disc diameter of fixation, other diabetes related eye disease). 358 subjects underwent photography, 326 attended hospital clinic for ophthalmoscopy, and six were ungradable on photographs and biomicroscopy, leaving 320 for analysis. Of these 295 (91%) attended clinic within four months of photography. Sensitivity of detection of eye disease by photography was 89% (95% confidence interval 80% to 98%), significantly better than for direct ophthalmoscopy (65% (51% to 79%)). Analysis of patients ...Continue Reading

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References

May 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·M J BuxtonS B Dudbridge
Aug 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·N Wareham, R Greenwood
Feb 1, 1990·Diabetic Medicine : a Journal of the British Diabetic Association·D RogersJ S Yudkin
Nov 1, 1986·British Medical Journal·R WilliamsG Thompson
Nov 1, 1988·The British Journal of Ophthalmology·R MohanH M Mather
Apr 6, 1985·British Medical Journal·C J Burns-Cox, J C Hart
Mar 1, 1984·Zhonghua yi xue za zhi·C F Zhang
Jun 18, 1982·JAMA : the Journal of the American Medical Association·E J SussmanK A Soper
Jun 11, 1994·BMJ : British Medical Journal·D G Altman, J M Bland
Jan 16, 1993·BMJ : British Medical Journal·G P LeeseJ Coleiro

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Citations

Apr 25, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jenny C Y LungHenry H L Chan
Jan 1, 2003·Survey of Ophthalmology·Donald S Fong
Jan 5, 2002·Diabetes Research and Clinical Practice·Teruo ShibaRyoko Hagura
Jun 6, 2000·Computer Methods and Programs in Biomedicine·D J TaylorJ E Tooke
Mar 1, 1997·Endocrinology and Metabolism Clinics of North America·H C Barry, M H Ebell
Jun 13, 2003·Clinical Cornerstone·Susan Lightman, Hamish M Towler
Dec 12, 2001·The Australian Journal of Rural Health·D Mak, A J Plant
Aug 13, 1999·Diabetic Medicine : a Journal of the British Diabetic Association·V M BryantR V Hague
Apr 25, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·E M KohnerUNKNOWN UK Prospective Diabetes Study (IKPDS) Group
Sep 5, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·S A HulmeP W Joyce
Oct 3, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·G P LeeseA Ellingford
Mar 22, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·N YounisJ R Vora
Nov 15, 2007·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Rajiv RamanTarun Sharma
Jun 19, 2004·The British Journal of Ophthalmology·H MurgatroydG P Leese
Mar 1, 1997·The British Journal of Ophthalmology·H Hirvelä, L Laatikainen
Jul 22, 1999·The British Journal of Ophthalmology·L D GeorgeR L Ollerton
Feb 17, 1996·BMJ : British Medical Journal·M Hickey-Dwyer, S Ellerby
Jun 16, 2000·BMJ : British Medical Journal·M JamesS P Harding
Nov 7, 2000·Quality in Health Care : QHC·A MelvilleA Hutchinson
Jul 4, 2013·BMC Medicine·Philip I BurgessNicholas A V Beare
Feb 21, 2007·Journal of Rehabilitation Research and Development·Paul R ConlinAdam W Darkins
Jun 26, 2014·PloS One·Elisa Martín-MerinoLuis Alberto García-Rodríguez
Mar 15, 2005·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·T R CarmichaelW J Kalk

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