Sensitivity and Stability of Functional Vision Tests in Detecting Subtle Changes Under Multiple Simulated Conditions.

Translational Vision Science & Technology
Zhipeng ChenJinrong Li

Abstract

To explore whether subtle changes in visual quality can be detected using different measures of visual function against the quick contrast sensitivity function test (quick CSF). Sixty participants, aged 17 to 34 years, were enrolled. Participants' vision was degraded by 0.25 D undercorrection (0.25 D), 60% neutral density filter brightness reduction (60% ND), and 0.8 Bangerter foil optical diffusion (0.8BAN). Visual function tests including visual acuity and contrast sensitivity (CSV-1000E and quick CSF) were measured with participant's best-corrected vision and under simulated visual degradation conditions. Test sensitivities in detecting differences were compared. Statistically significant visual acuity degradation was observed in the 0.8BAN condition only (Pcorrected < 0.001). With CSV-1000E and outliers removed, significant CS degradation was observed in all spatial frequencies, area under log CSF (AULCSF) in the 0.8BAN condition (Pcorrected < 0.001 for all), medium and high spatial frequencies and AULCSF in the 60%ND condition (Pcorrected,6cpd = 0.002, Pcorrected,12cpd = 0.005, Pcorrected,18cpd = 0.001, Pcorrected,AULCSF < 0.001) and the 0.25 D condition (Pcorrected,6cpd = 0.011, Pcorrected,12cpd = 0.013, Pcorrected,18cpd ...Continue Reading

References

Mar 1, 1989·Journal of Cataract and Refractive Surgery·L F Jindra, V Zemon
Jan 1, 1988·Ophthalmology·M F Marmor, A Gawande
Dec 1, 1987·Brain : a Journal of Neurology·I Bodis-WollnerM Yahr
Oct 1, 1987·The British Journal of Ophthalmology·C Owsley, M E Sloane
May 1, 1983·American Journal of Optometry and Physiological Optics·J P Comerford
Sep 1, 1984·Archives of Ophthalmology·D S Loshin, J White
Nov 1, 1984·The British Journal of Ophthalmology·J E RossD D Clarke
Feb 1, 1983·Perception & Psychophysics·A B Watson, D G Pelli
Jul 1, 1982·American Journal of Ophthalmology·F L Ferris, R D Sperduto
Nov 1, 1993·Optometry and Vision Science : Official Publication of the American Academy of Optometry·D ReganB B Fresco
Sep 24, 1999·Vision Research·L L Kontsevich, C W Tyler
Oct 27, 2004·Investigative Ophthalmology & Visual Science·Nayori YamaneTetsuro Oshika
May 16, 2006·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jens BührenThomas Kohnen
Aug 19, 2007·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Bettina HohbergerFolkert K Horn
Apr 2, 2008·Investigative Ophthalmology & Visual Science·Aliya HotWilliam H Swanson
Apr 10, 2010·Journal of Vision·Luis Andres LesmesThomas D Albright
Jul 17, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Susan A KellyStephanie Klemencic
Feb 23, 2013·Proceedings of the National Academy of Sciences of the United States of America·Sergei GepshteinThomas D Albright
Jan 23, 2014·Proceedings of the National Academy of Sciences of the United States of America·Amy KaliaPawan Sinha
Jul 6, 2014·Journal of Vision·Robert RosénPeter Unsbo
Jul 15, 2015·Journal of Vision·Fang HouZhong-Lin Lu
Jun 27, 2017·IEEE Journal of Biomedical and Health Informatics·Michael DorrLuis A Lesmes
Nov 28, 2018·Translational Vision Science & Technology·Haiyan ZhengFang Hou

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