PMID: 9529444Apr 8, 1998Paper

Sensitivity in detection of hypervascular hepatocellular carcinoma by helical CT with intra-arterial injection of contrast medium, and by helical CT and MR imaging with intravenous injection of contrast medium

Acta Radiologica
M HoriH Nakamura

Abstract

To determine the effectiveness of i.a. contrast-enhanced helical CT and of i.v. contrast-enhanced helical CT and MR imaging, in detecting hypervascular hepatocellular carcinoma (HCC). Fifty patients with 125 hypervascular HCC nodules underwent helical CT both during arterial portography (CTAP) and during hepatic arteriography (CTHA). Helical CT and MR imaging of the entire liver with i.v. administration of contrast medium were also performed. Helical CT images were obtained at 30-33 s (arterial-phase CT) and at 5 min (equilibrium-phase CT) after the initiation of an i.v. bolus injection of contrast medium. After T1- and T2-weighted spin-echo MR imaging, gradient-echo images during breath-holding were obtained prior to and 20 s, 1 min, and 2 min after the bolus administration of 0.1 mmol/kg of gadopentetate dimeglumine (dynamic MR). The sensitivity and positive predictive value of the various techniques were evaluated and compared. In terms of sensitivity for hypervascular HCC nodules of less than 1 cm in diameter, CTAP (90%) and CTHA (88%) were significantly superior to dynamic MR imaging (44%), arterial-phase CT (39%), spin-echo MR imaging (20%), and equilibrium-phase CT (7%) (p < 0.001). However, there was no significant diff...Continue Reading

Citations

May 1, 2002·European Journal of Gastroenterology & Hepatology·Victor de LédinghenJacques Drouillard
Jul 25, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yasuharu ImaiHironobu Nakamura
Jan 31, 2002·World Journal of Gastroenterology : WJG·Li LiLin Chen
Nov 3, 2009·European Radiology·Akihiro TanimotoLuigi Grazioli
Nov 20, 2002·Journal of Computer Assisted Tomography·Masatoshi HoriHironobu Nakamura
Sep 1, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Lewis R RobertsKhaled Mohammed
Sep 3, 2002·Journal of Magnetic Resonance Imaging : JMRI·Hiroshi YoshiokaYuji Itai
Jan 24, 2003·AJR. American Journal of Roentgenology·Yumi NoguchiHironobu Nakamura
Feb 26, 2010·Japanese Journal of Radiology·Motoki NakaiKazushi Kishi
Jan 5, 2021·Abdominal Radiology·Alex LionbergOsman Ahmed

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