Sensitivity of expanded-criteria donor kidneys to cold ischaemia time

Clinical Transplantation
Thomas D JohnstonDinesh Ranjan

Abstract

The United Network for Organ Sharing (UNOS), working in conjunction with organ procurement organizations and transplant programmes, has recently defined a class of cadaver kidney grafts for special allocation procedures to enhance utilization of those organs. The criteria defining these expanded-criteria donor (ECD) kidneys are donor age > or = 60 yr or donor age between 50 and 59 yr plus two of the following characteristics: donor history of cerebrovascular accident (CVA), donor history of hypertension (htn), and elevated creatinine (>1.5) at any time during donor management. Kidney grafts from ECD donors carry an increased relative risk of non-function compared to other cadaver kidney grafts. The goal of the special allocation procedure is to reduce the time associated with placement by matching ECD grafts with patients previously designated as being willing to accept them. In assessing the potential impact of these allocation procedures, the sensitivity of ECD grafts to cold ischaemia time (CIT) became of great significance. Specifically, we questioned whether minimization of CIT might reduce the relative risk of poor graft function, justifying reduction of the geographical range of placement and thereby reducing the time th...Continue Reading

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References

Apr 1, 1996·Surgery·L E RatnerJ S Bender
Jan 5, 2000·Kidney International·A O OjoF K Port
Aug 1, 2000·Kidney International·H BoomL C Paul
Dec 20, 2000·Transplantation Proceedings·R D Guttmann
Sep 24, 2002·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Bruce R RosengardFrancis L Delmonico
Dec 25, 2002·Transplantation·Steven M RudichHerwig-Ulf Meier-Kriesche
Jun 28, 2003·Transplantation·Mark A SchnitzlerZoltan Kalo
Jul 19, 2003·Clinical Transplantation·Antonio López-Navidad, Francisco Caballero

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Citations

Feb 1, 2012·World Journal of Urology·Javier BarbaIgnacio Pascual
Jul 4, 2012·International Urology and Nephrology·Anja GallinatGeorgios C Sotiropoulos
May 7, 2011·Critical Care : the Official Journal of the Critical Care Forum·Maria E HollmenKaija T Salmela
Feb 9, 2012·Transplantation Proceedings·Y H KimD J Han
Jul 11, 2009·Néphrologie & thérapeutique·Odette AbbadieBruno Hurault de Ligny
Aug 30, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Julio PascualJohn D Pirsch
Nov 29, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Juha P PeräsaariJussi M Merenmies
Oct 11, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Jonathan T CarterSandy Feng
Aug 18, 2005·BJU International·Pádraig J A DalyR William G Watson
Jun 13, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J F JohnsonA A House
Apr 21, 2006·Transplant International : Official Journal of the European Society for Organ Transplantation·Paulo N A MartinsStefan G Tullius
Jul 11, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J D ScholdH-U Meier-Kriesche
May 12, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L MatsuokaR Selby
Jan 18, 2006·Advances in Chronic Kidney Disease·Matthew J Koch
Jan 3, 2006·Transplantation Proceedings·D Truan CachoR Gutiérrez del Pozo
Jan 11, 2017·Transplantation·María José Pérez-SáezJulio Pascual
Sep 18, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·UNKNOWN European Renal Best Practice Transplantation Guideline Development Group
Apr 11, 2018·Current Opinion in Organ Transplantation·Catherine G Min, Klearchos K Papas
Aug 8, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rosana GelpiFritz Diekmann
Dec 24, 2004·Current Opinion in Critical Care·Patrick PeetersNorbert Lameire
Jul 5, 2011·The International Journal of Artificial Organs·Imad AbboudDenis Glotz

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