PMID: 490787Nov 9, 1979Paper

Sensitivity of mammography and physical examination of the breast for detecting breast cancer

JAMA : the Journal of the American Medical Association
M J HicksA J Present

Abstract

Mammography and physical examination of the breast are evaluated as screening instruments for detecting breast cancer based on local biopsy data obtained from women enrolled in a national breast cancer screening program. One hundren thirteen cancers (15.5%) of women who underwent biopsy) were detected. The individual sensitivities of mammography and physical examination for detecting breast cancer are 62% and 24%, respectively. The sensitivity of the two methods combined is 75% (85 of 113). Thirty-seven cancers were in situ or minimally invasive (less than or equal to 1 cm in greatest dimension). Eighty-one percent (30 of 37) of these small cancers were detected by screening, and they comprised 35% (30 of 85) of all cancers detected by mammography, physical examination, or both. Improved survival is anticipated due to this high rate of discovery of small cancers.

Citations

Dec 19, 2002·American Journal of Surgery·Atul K MadanDerrick J Beech
Feb 1, 1996·Journal of General Internal Medicine·M M McDermottA W Rademaker
May 1, 1991·Breast Cancer Research and Treatment·J S GroveG Low
Apr 1, 1992·Cancer·D P Winchester

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