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Sensitivity of quantitative traits to mutational effects, number of loci, and population history

bioRxiv

Aug 29, 2014

Joshua G. Schraiber, Michael J. Landis

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Abstract

When models of quantitative genetic variation are built from population genetic first principles, several assumptions are often made. One of the most important assumptions is that traits are controlled by many genes of small effect. This leads to a prediction of a Gaussian trait distrib...read more

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  • Sensitivity of quantitative traits to mutational effects, number of loci, and population history

    bioRxiv

    Aug 29, 2014

    Joshua G. Schraiber, Michael J. Landis

    PMID: 990008540

    DOI: 10.1101/008540

    Abstract

    When models of quantitative genetic variation are built from population genetic first principles, several assumptions are often made. One of the most important assumptions is that traits are controlled by many genes of small effect. This leads to a prediction of a Gaussian trait distrib...read more

    Mentioned in this Paper

    Animal Cancer Model
    Simulation
    Population Group
    Tail
    Genetic Loci
    15
    1

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