PMID: 2486526Jul 1, 1989Paper

Sensitivity of the culture of circulating leukocytes in the detection of Leishmania in the peripheral blood of patients with tegumentary leishmaniasis

Revista Da Sociedade Brasileira De Medicina Tropical
F T SilveiraR R Braga

Abstract

The possible presence of Leishmania in the peripheral blood of 60 patients with American cutaneous leishmaniasis was investigated by the culture of circulating leucocytes. Patients were selected with a variety of clinical forms of the disease and in different evolutionary stages of infection. Biopsies of skin and/or mucosal lesions were made in order to isolate the parasites, which were identified using monoclonal antibodies. 40 isolations were obtained, including 5 of Leishmania (Viannia) braziliensis, 3 L. (V.) guyanesis, 1 L. (V.) lainsoni, 13 L. (Leishmania) amazonensis and 18 which could only be identified as parasites of the braziliensis complex. Cultures of circulanting leucocytes were consistently negative, and the authors conclude that this method is of little use in diagnosis of cutaneous or mucocutaneous leishmaniasis.

References

Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·C A Cuba-CubaP D Marsden
Mar 1, 1981·American Journal of Clinical Pathology·J H BowdreD E Tart

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Citations

Apr 1, 1993·Revista Da Sociedade Brasileira De Medicina Tropical·C E GalvãoJ M Costa
Jul 1, 1993·Revista Da Sociedade Brasileira De Medicina Tropical·M A MoraesJ B Santos
Jun 12, 2002·Transactions of the Royal Society of Tropical Medicine and Hygiene·Sergio G CoutinhoAlda Maria Da-Cruz
Jun 13, 2006·Transactions of the Royal Society of Tropical Medicine and Hygiene·Patricia de Oliveira CameraClaude Pirmez
Jan 1, 1992·Transactions of the Royal Society of Tropical Medicine and Hygiene·M K HowardM A Miles
Jun 30, 2005·Parasitology Research·Maria de Fátima MadeiraMauro C A Marzochi

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