Sensitivity of the estimated air pollution-respiratory admissions relationship to statistical model choice

International Journal of Environmental Health Research
Bircan Erbas, Rob J Hyndman

Abstract

The objective of this study was to demonstrate the methodological shortcomings of currently available analytical methods for single-city time series data. We analyzed daily Chronic Obstructive Pulmonary Disease (COPD) and daily asthma hospital admissions in Melbourne, Australia from July 1989 to December 1992. Air pollution data comprised nitrogen dioxide, ozone and sulphur dioxide and air particles index consistent with particulates between 0.1 and 1 microm in aerodynamic diameter. Statistical analyses were performed using generalized linear models, generalized additive models, Poisson autoregressive models and transitional regression models. The estimated effect of nitrogen dioxide on COPD hospital admissions was similar across the different statistical models, RR = 1.06 (95% CI 1.01-1.11). Similarly the estimated effect of nitrogen dioxide on asthma hospital admissions was also consistent, RR = 1.05 (95% CI 1.01-1.09). However, the effects of ozone, air particles index and sulphur dioxide were highly sensitive to model specification for both COPD and asthma hospital admissions. In single-city studies of air pollution and respiratory disease, very different conclusions can be drawn from competing models. Furthermore, real tim...Continue Reading

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Citations

Feb 28, 2007·Health Care Management Science·Steven J Littig, Mark W Isken
Jul 7, 2007·International Journal of Environmental Health Research·Ahmed S Squalli HoussainiMohammed N Benchekroun
Jul 28, 2018·Aesthetic Surgery Journal·Tiffany N S BallardJeffrey M Kenkel
Jul 23, 2011·Environmental Research Letters : ERL [Web Site]·Meng JiMichelle L Bell
Mar 22, 2018·Environmental Science and Pollution Research International·Zili ZhangWenju Lu
Nov 8, 2013·Ciência & saúde coletiva·Cleber Nascimento do Carmo, Sandra de Souza Hacon
Jun 10, 2021·Internal Medicine Journal·Clare M WalterLuke D Knibbs

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