Sensitivity to isopropyl alcohol

Contact Dermatitis
E Ludwig, B M Hausen

Abstract

Positive patch test reactions to isopropyl alcohol in connection with proved allergy to ethyl alcohol have already been published. A case of allergy to isopropyl alcohol with positive reactions to isopropanol (unpurified test material) and negative reactions to ethanol and methanol has also been reported. We report a case of a occupationally acquired sensitivity to isopropyl alcohol in which, on testing with gas chromatographically purified material, positive patch test reactions were found to 1-propanol, 1-butanol, 2-propanol, 2-butanol and methanal (formaldehyde) but not to the primary alcohols methanol, ethanol and amyl alcohol; not to the aldehydes acetal (acetaldehyde) and butanal; nor to the ketones acetone, butanon and isobutyl ketone, nor to methanoic (formic)acid. A tentative explanation for this peculiar pattern of reactions is given.

References

Jan 1, 1975·Contact Dermatitis·W G van Ketel, K N Tan-Lim
Nov 1, 1968·Archives of Dermatology·C Wasilewski
Jul 1, 1961·The Journal of Allergy·C C DREVETS, P M SEEBOHM

Citations

Nov 1, 1995·Journal of Applied Toxicology : JAT·S Dhillon, R Von Burg
Apr 5, 2012·Pediatric Dermatology·Elnaz F FirozIsaac Brownell
Nov 1, 1993·British Journal of Industrial Medicine·M A Flyvholm
Jun 1, 1980·Clinical Toxicology·K E Andersen, H I Maibach
May 13, 2014·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·R J SlaughterL J Schep
Mar 1, 1978·The British Journal of Dermatology·B M Hausen, K H Schulz
Apr 8, 2004·The Australasian Journal of Dermatology·Emma StorerAnn Kupa
Jun 18, 2011·Contact Dermatitis·Juan García-GavínAn Goossens
Sep 3, 2014·The Australasian Journal of Dermatology·Julia Lai-KwonMei Mui Tam
Mar 21, 2017·Contact Dermatitis·Hilde M BoskerMarie Louise Schuttelaar
Jul 19, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Margaret ChouTamara Lazic Strugar

Related Concepts

1-Propanol
Contact Hypersensitivity
Dose-Response Relationship, Drug
Patch Tests

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