Sensitivity to isopropyl alcohol

Contact Dermatitis
E Ludwig, B M Hausen


Positive patch test reactions to isopropyl alcohol in connection with proved allergy to ethyl alcohol have already been published. A case of allergy to isopropyl alcohol with positive reactions to isopropanol (unpurified test material) and negative reactions to ethanol and methanol has also been reported. We report a case of a occupationally acquired sensitivity to isopropyl alcohol in which, on testing with gas chromatographically purified material, positive patch test reactions were found to 1-propanol, 1-butanol, 2-propanol, 2-butanol and methanal (formaldehyde) but not to the primary alcohols methanol, ethanol and amyl alcohol; not to the aldehydes acetal (acetaldehyde) and butanal; nor to the ketones acetone, butanon and isobutyl ketone, nor to methanoic (formic)acid. A tentative explanation for this peculiar pattern of reactions is given.


Jan 1, 1975·Contact Dermatitis·W G van Ketel, K N Tan-Lim
Nov 1, 1968·Archives of Dermatology·C Wasilewski
Jul 1, 1961·The Journal of Allergy·C C DREVETS, P M SEEBOHM


Nov 1, 1995·Journal of Applied Toxicology : JAT·S Dhillon, R Von Burg
Apr 5, 2012·Pediatric Dermatology·Elnaz F FirozIsaac Brownell
Nov 1, 1993·British Journal of Industrial Medicine·M A Flyvholm
Jun 1, 1980·Clinical Toxicology·K E Andersen, H I Maibach
May 13, 2014·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·R J SlaughterL J Schep
Mar 1, 1978·The British Journal of Dermatology·B M Hausen, K H Schulz
Apr 8, 2004·The Australasian Journal of Dermatology·Emma StorerAnn Kupa
Jun 18, 2011·Contact Dermatitis·Juan García-GavínAn Goossens
Sep 3, 2014·The Australasian Journal of Dermatology·Julia Lai-KwonMei Mui Tam
Mar 21, 2017·Contact Dermatitis·Hilde M BoskerMarie Louise Schuttelaar
Jul 19, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Margaret ChouTamara Lazic Strugar

Related Concepts

Contact Hypersensitivity
Dose-Response Relationship, Drug
Patch Tests

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.