Sensor-based systems for early detection of dementia (SENDA): a study protocol for a prospective cohort sequential study

BMC Neurology
Katrin MüllerClaudia Voelcker-Rehage

Abstract

Dementia and cognitive decline are serious social and economic burdens. An increase in the population of older people, as well as longer lifespans mean that numbers of dementia cases are exponentially rising. Neuropathological changes associated with dementia are thought to appear before the clinical manifestation of cognitive symptoms, i.e., memory impairments. Further, some older adults (OA) experience cognitive decline before it can be objectively diagnosed. For optimal care of these patients, it is necessary to detect cognitive decline and dementia at an early stage. In this vein, motor, sensory, and neurophysiological declines could be promising factors if found to be present before the onset of cognitive impairment. Hence, the objective of the SENDA study is to develop a multi-dimensional sensor-based instrument that allows early detection of cognitive decline or dementia in OA with the help of cognitive, sensory, motor, and neurophysiological parameters before its clinical manifestation. In the cohort sequential study, participants are assigned to one of three study groups depending on their cognitive status: 1. cognitively healthy individuals (CHI), 2. subjectively cognitively impaired persons (SCI), or 3. (possible) mi...Continue Reading

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Citations

Apr 16, 2020·Frontiers in Physiology·Julian RudischClaudia Voelcker-Rehage
Aug 31, 2021·Frontiers in Aging Neuroscience·Stephanie FröhlichClaudia Voelcker-Rehage

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Software Mentioned

Power
LabView
SENDA
Kinect
Posturomed
Plus
CERAD
Optogait
XPCV XPCV - Cross Platform Computer Vision Framework

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