Sensorimotor Peripheral Nerve Function and the Longitudinal Relationship With Endurance Walking in the Health, Aging and Body Composition Study

Archives of Physical Medicine and Rehabilitation
Brittney S Lange-MaiaHealth, Aging and Body Composition Study

Abstract

To determine whether lower extremity sensorimotor peripheral nerve deficits are associated with reduced walking endurance in older adults. Prospective cohort study with 6 years of follow-up. Two university research clinics. Community-dwelling older adults enrolled in the Health, Aging and Body Composition Study from the 2000-2001 annual clinical examination (N=2393; mean age ± SD, 76.5±2.9y; 48.2% men; 38.2% black) and a subset with longitudinal data (n=1178). Not applicable. Participants underwent peripheral nerve function examination in 2000-2001, including peroneal motor nerve conduction amplitude and velocity, vibration perception threshold, and monofilament testing. Symptoms of lower extremity peripheral neuropathy included numbness or tingling and sudden stabbing, burning, pain, or aches in the feet or legs. The Long Distance Corridor Walk (LDCW) (400 m) was administered in 2000-2001 and every 2 years afterward for 6 years to assess endurance walking performance over time. In separate, fully adjusted linear mixed models, poor vibration threshold (>130 μm), 10-g and 1.4-g monofilament insensitivity were each associated with a slower 400-m walk completion time (16.0 s, 14.4s, and 6.9 s slower, respectively; P<.05 for each)....Continue Reading

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Citations

Mar 16, 2016·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Luigi FerrucciDiana Kuh
Sep 25, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kelly R YlitaloCarrie A Karvonen-Gutierrez
May 15, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Ranjani N MoorthiElsa S Strotmeyer
Mar 18, 2020·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Masafumi NozoeKyoshi Mase

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