Sensory and cognitive effects of acute exposure to hydrogen sulfide

Environmental Health Perspectives
Nancy FiedlerPaul Lioy

Abstract

Some epidemiologic studies have reported compromised cognitive and sensory performance among individuals exposed to low concentrations of hydrogen sulfide (H2S). We hypothesized a dose-response increase in symptom severity and reduction in sensory and cognitive performance in response to controlled H2S exposures. In separate exposure sessions administered in random order over three consecutive weeks, 74 healthy subjects [35 females, 39 males; mean age (+/- SD) = 24.7 +/- 4.2; mean years of education = 16.5 +/- 2.4], were exposed to 0.05, 0.5, and 5 ppm H2S. During each exposure session, subjects completed ratings and tests before H2S exposure (baseline) and during the final hour of the 2-hr exposure period. Dose-response reduction in air quality and increases in ratings of odor intensity, irritation, and unpleasantness were observed. Total symptom severity was not significantly elevated across any exposure condition, but anxiety symptoms were significantly greater in the 5-ppm than in the 0.05-ppm condition. No dose-response effect was observed for sensory or cognitive measures. Verbal learning was compromised during each exposure condition. Although some symptoms increased with exposure, the magnitude of these changes was rela...Continue Reading

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Citations

Apr 30, 2016·International Journal of Occupational and Environmental Health·Eunjung LimJames Davis
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Dec 18, 2014·Environmental Science & Technology·Andrea M Dietrich, Gary A Burlingame

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AccuSway Computerized Platform System

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