Sensory Ganglionopathy and the Blink Reflex: Electrophysiological Features

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
Taimour AlamDasappaiah G Rao

Abstract

Sensory ganglionopathy (SG) is characterised by asymmetrical sensory fibre degeneration, with the primary pathology occurring at the level of the dorsal root ganglion. It is seen in the context of autoimmune, paraneoplastic, and degenerative disorders. There is limited literature examining the electrophysiological correlate of the trigeminal ganglion and associated pathways, the blink reflex (BR), in cases of SG. Previous work has suggested that the BR is preserved in cases of SG associated with paraneoplasia. The local clinical neurophysiology database was searched for patients diagnosed with SG from peripheral nerve conduction studies in whom the BR was performed. Twenty-six patients were included in the final analysis. Sjögren's syndrome constituted the most common SG aetiology (8/26), followed by idiopathic cases (7/26) and paraneoplasia (5/26). BR abnormalities were seen in 9 of the 26 patients (34.6%) across all aetiologies. No patients reported sensory disturbance in the distribution of the trigeminal nerve, indicating that the changes noted are subclinical. Three patients showed abnormality of the R1 response; in the remaining six patients, only R2 responses were affected. Subclinical abnormalities of both R1 and R2 can...Continue Reading

References

Dec 1, 1992·Muscle & Nerve·A A LeisM A Ross
Jul 1, 1991·Journal of Neurology·C De PablosJ Calleja
Dec 1, 1970·Journal of Neurology, Neurosurgery, and Psychiatry·B Shahani
Mar 27, 1999·Neurophysiologie clinique = Clinical neurophysiology·A Esteban
Dec 18, 2001·Diabetes/metabolism Research and Reviews·B NazlielB Koçer
May 24, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Benjamin Trujillo-HernándezClemente Vásquez
Jul 20, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·F GrausR Voltz
May 24, 2005·Lancet Neurology·Angelo SghirlanzoniGiuseppe Lauria
Jul 29, 2005·Brain : a Journal of Neurology·Keiko MoriGen Sobue
Aug 10, 2005·Neurophysiologie clinique = Clinical neurophysiology·Jean-Yves Hogrel
Jun 10, 2009·Brain : a Journal of Neurology·Jean-Philippe CamdessanchéJean-Christophe Antoine
Aug 26, 2010·Brain : a Journal of Neurology·Haruki KoikeGen Sobue
Sep 15, 2010·Neurology·M HadjivassiliouA G B Davies-Jones
Feb 15, 2011·Journal of the Neurological Sciences·Arnulf H Koeppen
Jul 30, 2011·Current Opinion in Neurology·Haruki KoikeGen Sobue

❮ Previous
Next ❯

Citations

Jan 12, 2017·Cerebellum & Ataxias·Panagiotis ZisMarios Hadjivassiliou
Jan 4, 2018·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Iryna M Muzyka, Bachir Estephan
Oct 3, 2017·Continuum : Lifelong Learning in Neurology·Kelly Graham Gwathmey
May 10, 2019·BMJ : British Medical Journal·Kelly Graham Gwathmey, Kathleen T Pearson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Electromyography and Clinical Neurophysiology
K HessH H Schiller
Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging
Alfredo DamascenoAnamarli Nucci
Brain : a Journal of Neurology
Jean-Philippe CamdessanchéJean-Christophe Antoine
© 2022 Meta ULC. All rights reserved