Sensory neurons supplying touch domes near the body midlines project bilaterally in the thoracic spinal cord of rats

The Journal of Comparative Neurology
C L Smith

Abstract

Sensory neurons that project bilaterally to laminae III-V of the dorsal horns in the thoracic spinal cord of rats were described in a previous anatomical study. The electrophysiological experiments reported here show that these neurons innervate skin near the dorsal and ventral midlines. Three series of experiments were undertaken: the regions of skin supplied by subdivisions of thoracic nerves were mapped by recording from the subdivisions while mechanically stimulating the skin; subdivisions containing the axons of contralaterally projecting sensory neurons were identified by antidromic activation from the contralateral dorsal horn; the receptive fields of individual sensory neurons and dorsal horn neurons were characterized by single-unit recording methods. Contralaterally projecting sensory neurons had axons in subdivisions of the thoracic nerves that supply skin adjacent to the body midlines. Their receptive fields were located near the dorsal or ventral midline but did not extend onto the contralateral side of the body. Most of the neurons were slowly adapting "type I" units supplying touch domes. Dorsal horn neurons receiving input from contralateral sensory neurons had receptive fields that overlapped the dorsal or vent...Continue Reading

References

Apr 1, 1979·Experimental Neurology·J L CulbersonP B Brown
Jun 15, 1979·The Journal of Comparative Neurology·M RéthelyiE R Perl
Aug 1, 1979·Experimental Neurology·M Devor, R Govrin-Lippmann
Nov 1, 1979·The Journal of Physiology·J B Munson, G W Sypert
Jan 1, 1975·Journal of Neurophysiology·P B Brown, J L Fuchs
Aug 1, 1973·The Journal of Comparative Neurology·J StoneS M Sherman
Jan 1, 1973·Brain, Behavior and Evolution·W I Welker
Apr 30, 1973·Experimental Brain Research·R N BryanW D Willis
Feb 1, 1969·The Journal of Physiology·A Iggo, A R Muir
Dec 1, 1967·The Journal of Comparative Neurology·K R Smith
May 1, 1968·Journal of Neurophysiology·J Leicester
Dec 1, 1968·The Journal of Physiology·B PomeranzW V Weber
Nov 1, 1968·Journal of Neurophysiology·P R BurgessR M Warren
Jan 1, 1968·Experimental Brain Research·A G Brown
Nov 1, 1968·The Journal of Comparative Neurology·E J Kirk
Aug 1, 1980·Journal of Neurophysiology·H R Koerber, P B Brown
Mar 1, 1960·Journal of Neurophysiology·P D WALL
Jun 1, 1952·The Journal of Comparative Neurology·B REXED

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Citations

Sep 13, 2001·The European Journal of Neuroscience·A M RitterH R Koerber
Jan 15, 1991·The Journal of Comparative Neurology·C F Marfurt, D M Rajchert
Jun 22, 1990·The Journal of Comparative Neurology·A R BlightR B Borgens
Apr 20, 2019·Nature Reviews. Neuroscience·Alain Chédotal
Jan 22, 1989·The Journal of Comparative Neurology·B M DavisS A Scott
May 15, 1995·The Journal of Comparative Neurology·K Mirnics, H R Koerber
Nov 8, 1989·The Journal of Comparative Neurology·L A RitzS M Bailey
Jul 1, 1992·The Journal of Comparative Neurology·J P GuillemotF Lepore
Oct 1, 1993·The Journal of Comparative Neurology·W E GladfelterP B Brown

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