PMID: 19605005Aug 1, 1977

Sensory responses in motor cortex neurons during precise motor control

Neuroscience Letters
E V Evarts, C Fromm

Abstract

Precentral neurons whose activity changed with precisely controlled small supination-pronation movements almost invariably showed sensory responses to small perturbations which pronated or supinated the forearm in conscious monkeys. Conversely, most units failing to show changes with small movements but being recruited with large ballistic movements were unaffected by these kinesthetic inputs. Moreover, perturbations which yielded intense short-latency unit responses when delivered during postural stability usually failed to modify unit activity when delivered during a ballistic movement. It is suggested that sensory feedback continuously modulates motor cortex neuron discharge during accurate positioning and precise fine movement, whereas during ballistic movements such modulation is greatly attenuated.

References

Dec 1, 1975·Journal of Neurology, Neurosurgery, and Psychiatry·M HallettR R Young
Aug 1, 1977·Neuroscience Letters·C Fromm, E V Evarts

Citations

Mar 1, 2012·Experimental Brain Research·J Andrew Pruszynski, Stephen H Scott
Feb 1, 1980·Electroencephalography and Clinical Neurophysiology·F CianciaJ M Coquery
Nov 1, 1985·Electroencephalography and Clinical Neurophysiology·D J CrammondJ T Murphy
Jan 1, 1986·Neuroscience and Biobehavioral Reviews·M C Wetzel
May 1, 1980·Brain Research·E G Jones, R Porter
Nov 1, 1985·Electroencephalography and Clinical Neurophysiology·R RauchC C Boylls
Jan 1, 1989·Progress in Neurobiology·A Prochazka
Jun 1, 1990·Brain Research Bulletin·L D GuginoS D Stoney
Feb 26, 2014·Journal of Cognitive Neuroscience·Laura DipietroHermano I Krebs
Dec 1, 1991·Electroencephalography and Clinical Neurophysiology·P M RossiniE Ferrari
Jun 24, 2015·Neuropsychologia·Rochelle Ackerley, Anne Kavounoudias
Dec 24, 2013·Brain and Behavior·Masataka SuzukiRyusuke Kakigi
Jan 1, 1986·Brain and Language·H SussmanP MacNeilage
Jan 1, 1993·Somatosensory & Motor Research·B Y CooperC J Vierck
May 22, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Daisuke SatoAtsuo Maruyama
Jan 10, 2001·Annual Review of Psychology·D A RosenbaumR O Gilmore
Aug 1, 1982·Experimental Neurology·R W Angel, R C Malenka
Sep 1, 2016·Journal of Neural Engineering·Won Joon SohnTerence D Sanger
Jan 1, 1987·Journal of Neurology, Neurosurgery, and Psychiatry·H H FriedemannM Bacher
Aug 4, 2005·Experimental Brain Research·Stefano TamburinGiampietro Zanette
Jun 28, 2018·Journal of Neurophysiology·Kristin M QuickAaron P Batista
Oct 9, 2015·Journal of Neurophysiology·Jeffrey WeilerJ Andrew Pruszynski
Oct 1, 1989·Perceptual and Motor Skills·A M Baylor, N Benjuya
Nov 10, 2017·Journal of Neurophysiology·Jeffrey WeilerJ Andrew Pruszynski
Nov 14, 2008·Journal of Neurophysiology·Troy M HerterStephen H Scott
Aug 19, 2016·Journal of Neurophysiology·Jeffrey WeilerJ Andrew Pruszynski
Jun 16, 2017·Journal of Neurophysiology·Mohsen OmraniPaul D Cheney
May 24, 2017·Proceedings of the National Academy of Sciences of the United States of America·Stephanie K RièsRobert T Knight

Related Concepts

Forearm
Monkeys
Motor Neurons
Neurons
Esthesia
Sensory Feedback
Modulated
Positioning Attribute
Neuromuscular Process Controlling Posture

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