Sentence production in Parkinson's disease

Clinical Linguistics & Phonetics
Jessica DickJiyeon Lee

Abstract

While growing evidence reports changes in language use in non-demented individuals with Parkinson's disease (PD), the presence and nature of the deficits remain largely unclear. Researchers have proposed that dysfunctioning fronto-basal ganglia circuit results in impaired grammatical processes, predicting qualitatively similar language impairments between individuals with PD and agrammatic Broca's aphasia, whereas others suggest that PD is not associated with language-specific grammatical impairment. In addition, there is a paucity of research examining syntactic production in PD at the sentence-level. This study examined sentence production of individuals with PD, healthy older adults, and individuals with agrammatic Broca's aphasia. In Experiment 1, using a Cinderella story-telling task, proportion of grammatical sentences, number of embedded clauses and production of verb arguments in sentences were examined. In Experiment 2, a structured sentence elicitation task was used in which syntactic complexity of sentences (canonical vs. non-canonical word order) was systematically manipulated while minimizing demands for non-syntactic processing. Only the participants with agrammatic Broca's aphasia showed significantly impaired sy...Continue Reading

References

Jun 1, 1990·The Journal of Nervous and Mental Disease·P LiebermanL S Feldman
Oct 1, 1989·Brain and Language·E M SaffranM F Schwartz
Jun 4, 1999·Brain : a Journal of Neurology·A D FriedericiS A Kotz
Nov 7, 1999·Journal of Clinical and Experimental Neuropsychology·A L PiattA I Tröster
Feb 24, 2001·Journal of Speech, Language, and Hearing Research : JSLHR·L L Murray
Apr 17, 2001·The Behavioral and Brain Sciences·D Caplan, G S Waters
Aug 31, 2001·Brain and Cognition·L L Murray, L P Lenz
Sep 28, 2001·The Journal of Head Trauma Rehabilitation·G HotzN W Nelson
Oct 5, 2001·Nature Reviews. Neuroscience·M T Ullman
Jan 10, 2002·Journal of Clinical and Experimental Neuropsychology·W L ArnottP A Silburn
Jan 10, 2002·Journal of Clinical and Experimental Neuropsychology·D A CoplandB E Murdoch
Mar 19, 2002·Brain and Language·Murray GrossmanHoward I Hurtig
Jan 23, 2003·Movement Disorders : Official Journal of the Movement Disorder Society·Patrice PéranDominique Cardebat
Feb 1, 2003·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Stefan FrischAngela D Friederici
Dec 31, 2003·Journal of Speech, Language, and Hearing Research : JSLHR·Cynthia K ThompsonJana Sobecks
Jan 24, 2004·Journal of the International Neuropsychological Society : JINS·Sonja A KotzAngela D Friederici
Jun 3, 2004·Brain and Language·Roelien Bastiaanse, Ron van Zonneveld
Jan 22, 2005·Brain : a Journal of Neurology·C E LongworthL K Tyler
Dec 6, 2005·Brain and Language·Cecile A Marczinski, Andrew Kertesz
Dec 16, 2005·Neuropsychological Rehabilitation·Elizabeth RochonJoanne Scofield
Aug 3, 2006·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Michael T Ullman
Mar 24, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Katrien S F ColmanRoelien Bastiaanse
Apr 28, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·David A CoplandHelen J Chenery
May 19, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Peter F Dominey, Toshio Inui
May 19, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Roelien Bastiaanse, Klaus L Leenders
May 29, 2009·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Jesse Hochstadt
Apr 1, 2004·Journal of Neurolinguistics·Miseon Lee, Cynthia K Thompson
Dec 28, 2011·Brain and Language·Shiao-Hui ChanThomas G Bever
Mar 22, 2013·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Cynthia K ThompsonSladjana Lukic
Apr 25, 2015·Journal of Speech, Language, and Hearing Research : JSLHR·Jiyeon LeeCynthia K Thompson
Apr 7, 2017·Journal of Speech, Language, and Hearing Research : JSLHR·Jiyeon Lee

❮ Previous
Next ❯

Citations

Jul 23, 2020·American Journal of Speech-language Pathology·Meghan Darling-White, Jessica E Huber
Nov 4, 2020·Journal of Speech, Language, and Hearing Research : JSLHR·Binna Lee, Diana Van Lancker Sidtis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal ganglia in Parkinson's disease (MDS)

The basal ganglia is comprised of the neostriatum, the external and internal pallidal segments, the subthalamic nucleus, the substantia nigra pars reticulata, and the pars compacta of the substantia nigra. The basal ganglia circuitry is responsible for the correct execution of voluntary movements and is implicated in Parkinson's disease. Here is the latest research investigating the basal ganglia in Parkinson's disease.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.