Sentinel lymph node biopsy before or after neoadjuvant chemotherapy: pros and cons

Surgical Oncology Clinics of North America
Michael S Sabel

Abstract

This article summarizes the relative pros and cons surrounding the timing of sentinel lymph node (SLN) biopsy in patients undergoing neoadjuvant chemotherapy. Several institutions initiated prospective trials of SLN biopsy performed after neoadjuvant chemotherapy in conjunction with a completion axillary lymph node dissection, with the goal of ultimately showing that SLN biopsy could be safely and accurately performed after the patient completed systemic therapy. Other institutions adopted a policy of performing SLN biopsy before initiation of chemotherapy. This avoided the issue surrounding the accuracy of SLN biopsy after chemotherapy and potentially provided information that might influence adjuvant therapy decisions. This article addresses the clinical questions regarding the 2 approaches including the accuracy of the procedure and the prognostic information gleaned.

References

Oct 2, 1997·The New England Journal of Medicine·J RagazI A Olivotto
Oct 1, 1998·The New England Journal of Medicine·D KragP Beitsch
Jun 8, 1999·The Journal of Surgical Research·D M MiltenburgF C Brunicardi
Dec 3, 1999·The British Journal of Surgery·A Y de KanterT Wiggers
Jul 13, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A E GiulianoR R Turner
Aug 15, 2000·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M FraileM A Broggi
Oct 14, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T M BreslinK K Hunt
Mar 27, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·U VeronesiG Viale
Nov 27, 2001·American Journal of Surgery·L TafraD R Lannin
Jan 5, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Thomas A BuchholzGabriel N Hortobagyi
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roman RouzierEdwige Bourstyn
Oct 18, 2002·American Journal of Surgery·Jovita U N OruwariBlake Cady
Oct 18, 2002·American Journal of Surgery·Maureen A ChungBlake Cady
Oct 18, 2002·American Journal of Surgery·Thomas B JulianNorman Wolmark
Jan 7, 2003·Archives of Surgery·J Michael GuentherTheodore X O'Connell
Mar 14, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·José Roberto M PiatoJosé Aristodemo Pinotti
May 8, 2003·Annals of Surgical Oncology·Brian D BadgwellWilliam E Burak
Jun 24, 2003·Clinical Nuclear Medicine·Adriano VigarioC A Buchpiguel
Jul 29, 2003·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·A HaidG Zimmermann
Jul 30, 2003·American Journal of Surgery·Michael S SabelLori J Pierce
Aug 9, 2003·The New England Journal of Medicine·Umberto VeronesiRoberto Gennari
Sep 23, 2003·Journal of Surgical Oncology·Roland ReitsamerEva Prokop
Feb 3, 2004·Journal of Surgical Oncology·Tomohiko AiharaYuichi Takatsuka
Sep 17, 2004·Japanese Journal of Clinical Oncology·Shigeru ImotoSatoshi Ebihara

❮ Previous
Next ❯

Citations

Apr 24, 2014·Future Oncology·John R Benson, Ismail Jatoi
Jun 24, 2014·Semergen·C Álvarez HernándezL Robles Díaz
May 21, 2013·Revista española de medicina nuclear e imagen molecular·A C Rebollo-AguirreS Menjón-Beltrán
Aug 8, 2012·Current Problems in Cancer·Alan Adolph Thomay
Jan 13, 2012·Surgical Oncology·Desiree D D'Angelo-DonovanNicholas J Petrelli
Jun 24, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G CanaveseA Catturich
Jun 17, 2011·Revista española de medicina nuclear e imagen molecular·A C Rebollo-AguirreN Olea-Serrano
Oct 14, 2016·The Lancet Oncology·Ismail JatoiMasakazu Toi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Cancer Genomics (Keystone)

Cancer genomics approaches employ high-throughput technologies to identify the complete catalog of somatic alterations that characterize the genome, transcriptome and epigenome of cohorts of tumor samples. Discover the latest research using such technologies in this feed.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.